Nadia Boshnak

TL;DR: This study uses CyTOF mass cytometry to characterize the immune populations of the naive mouse brain using 44 cell surface markers and demonstrates the phenotypic ranges of resident myeloid cells and identifies CD44 as a marker for infiltrating immune populations.

TL;DR: It is shown that chemogenetic activation of the brain’s reward system ventral tegmental area (VTA) can boost mice's immune function, confer anti-tumor immunity, and reduce tumor mass in experimental rodent models of lung carcinoma and melanoma.

TL;DR: In this paper, the brain's insular cortex (InsCtx) was shown to store immune-related information, and the brain can store and retrieve specific immune responses, extending the classical concept of immunological memory to neuronal representations.

TL;DR: In this paper, the authors investigated the impact of the local arm of the SNS in an inflammatory response in the colon and found that local activation of sympathetic fibers attenuated experimental colitis and reduced immune cell abundance.

TL;DR: It is shown that immune-related information is stored in the brain’s insular cortex (InsCtx) and that the brain can encode and initiate specific immune responses, extending the classical concept of immunological memory to neuronal representations of immunity.