N
Nadia Chabane
Researcher at French Institute of Health and Medical Research
Publications - 44
Citations - 4811
Nadia Chabane is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Autism & Superior temporal sulcus. The author has an hindex of 26, co-authored 43 publications receiving 4480 citations. Previous affiliations of Nadia Chabane include University of Paris & National Institutes of Health.
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Journal ArticleDOI
Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders.
Christelle M. Durand,Catalina Betancur,Tobias M. Boeckers,Juergen Bockmann,Pauline Chaste,Fabien Fauchereau,Gudrun Nygren,Maria Råstam,I. Carina Gillberg,Henrik Anckarsäter,Eili Sponheim,Hany Goubran-Botros,Richard Delorme,Nadia Chabane,Marie-Christine Mouren-Simeoni,Philippe de Mas,Eric Bieth,Bernadette Rogé,Delphine Héron,Lydie Burglen,Christopher Gillberg,Marion Leboyer,Thomas Bourgeron +22 more
TL;DR: It is reported that a mutation of a single copy of SHANK3 on chromosome 22q13 can result in language and/or social communication disorders.
Journal ArticleDOI
Abnormal melatonin synthesis in autism spectrum disorders
Jonas Melke,H Goubran Botros,Pauline Chaste,Catalina Betancur,Gudrun Nygren,Henrik Anckarsäter,Henrik Anckarsäter,Maria Råstam,Ola Ståhlberg,I. C. Gillberg,Richard Delorme,Nadia Chabane,M-C Mouren-Simeoni,Fabien Fauchereau,Christelle M. Durand,F Chevalier,X Drouot,Corinne Collet,J.M. Launay,Marion Leboyer,Christopher Gillberg,Thomas Bourgeron +21 more
TL;DR: Results indicate that a low melatonin level, caused by a primary deficit in ASMT activity, is a risk factor for autism spectrum disorders and support ASMT as a susceptibility gene for ASD and highlight the crucial role of melatonin in human cognition and behavior.
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Superior temporal sulcus anatomical abnormalities in childhood autism: a voxel-based morphometry MRI study
Nathalie Boddaert,Nadia Chabane,H. Gervais,Catriona D. Good,Muriel Le Bourgeois,Marie-Hélène Plumet,Catherine Barthélémy,Marie-Christine Mouren,Eric Artiges,Yves Samson,Francis Brunelle,Francis Brunelle,Richard S. J. Frackowiak,Monica Zilbovicius +13 more
TL;DR: An anatomical MRI study using optimized whole-brain voxel-based morphometry suggests that autism is associated with bilateral anatomical abnormalities localized in the superior temporal sulcus and are remarkably consistent with functional hypoperfusion previously reported in children with autism.
Journal ArticleDOI
Autism, the superior temporal sulcus and social perception
Monica Zilbovicius,Isabelle Meresse,Nadia Chabane,Francis Brunelle,Yves Samson,Nathalie Boddaert,Nathalie Boddaert +6 more
TL;DR: The hypothesis is that abnormalities in the superior temporal sulcus (STS) are highly implicated in ASD, and anatomical and functional anomalies occurring during early brain development could constitute the first step in the cascade of neural dysfunction underlying ASD.
Journal ArticleDOI
Perception of complex sounds: abnormal pattern of cortical activation in autism.
Nathalie Boddaert,Pascal Belin,Nadia Chabane,Jean-Baptiste Poline,Catherine Barthélémy,Marie-Christine Mouren-Simeoni,Francis Brunelle,Yves Samson,Monica Zilbovicius +8 more
TL;DR: Findings suggest that abnormal auditory cortical processing is implicated in the language impairments and the inadequate response to sounds typically seen in autism.