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Nam Jin Yoo
Researcher at Catholic University of Korea
Publications - 405
Citations - 13537
Nam Jin Yoo is an academic researcher from Catholic University of Korea. The author has contributed to research in topics: Frameshift mutation & Germline mutation. The author has an hindex of 63, co-authored 403 publications receiving 12692 citations. Previous affiliations of Nam Jin Yoo include Catholic University College, Kensington & The Catholic University of America.
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Journal ArticleDOI
ArrayCyGHt: a web application for analysis and visualization of array-CGH data
Su Young Kim,Suk Woo Nam,Sug Hyung Lee,Won Sang Park,Nam Jin Yoo,Jung Young Lee,Yeun-Jun Chung +6 more
TL;DR: ArrayCyGHt, therefore, provides an easy and fast tool for the analysis of copy number aberrations in any kinds of data format.
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Frameshift Mutations in Repeat Sequences of ANK3, HACD4, TCP10L, TP53BP1, MFN1, LCMT2, RNMT, TRMT6, METTL8 and METTL16 Genes in Colon Cancers
TL;DR: The data exhibit that cancer-related genes ANK3, HACD4, TP53BP1, MFN1, LCMT2, RNMT, TRMT6, METTL8 and METTL16 harbor mutational ITH as well as the frameshift mutations in CRC with MSI-H, which suggest that frameshIFT mutations of these genes might play a role in tumorigenesis through their inactivation in CRC.
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NF-κB signalling proteins p50/p105, p52/p100, RelA, and IKKε are over-expressed in oesophageal squamous cell carcinomas
TL;DR: The increased nuclear expressions of p50/105, p52/p100 and RelA as well as increased cytoplasmic expression of IKKε in the ESCC tissues compared to the normal squamous cells suggested that over‐expression of these proteins may be related to activation of the NF‐κB pathway and might play a role in the development of ESCC.
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Mapping of a new target region of allelic loss at 21q22 in primary gastric cancers.
Won Sang Park,Ro Ra Oh,Jik Young Park,Nam Jin Yoo,Sug Hyung Lee,Min Sun Shin,Su Young Kim,Young Sil Kim,Jong Heun Lee,Hong Sug Kim,Won G. An,Jung Young Lee +11 more
TL;DR: It is speculated that trefoil factor family 1 (TFF1), located in this narrow region, might be the most probable candidate gene involved in gastric cancer carcinogenesis.
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Frameshift mutations of vacuolar protein sorting genes in gastric and colorectal cancers with microsatellite instability.
TL;DR: The data indicate that frameshift mutations of VPS genes and losses of expression of Vps13A and Vps35 proteins are common in gastric cancers and colorectal cancers with high microsatellite instability and suggest that these alterations might contribute to development of cancers withhigh micros satellite instability by deregulating vacuolar protein sorting proteins.