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Won Sang Park
Researcher at Catholic University of Korea
Publications - 231
Citations - 11257
Won Sang Park is an academic researcher from Catholic University of Korea. The author has contributed to research in topics: Cancer & Gene. The author has an hindex of 58, co-authored 227 publications receiving 10501 citations. Previous affiliations of Won Sang Park include Chung-Ang University & The Catholic University of America.
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Journal ArticleDOI
PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas
Jong Woo Lee,Young Hwa Soung,Su Young Kim,Hae Woo Lee,Won Sang Park,Suk Woo Nam,Sang Ho Kim,Jung Young Lee,Nam Jin Yoo,Sug Hyung Lee +9 more
TL;DR: In this paper, the authors performed mutational analysis of the PIK3CA gene by polymerase chain reaction-single-strand conformation polymorphism assay in 668 cases of common human cancers, including hepatocellular carcinomas, acute leukemias, gastric carcinoma, breast carcinomas and non-small-cell lung cancers.
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Increased expression of histone deacetylase 2 is found in human gastric cancer
Jaehwi Song,Ji Heon Noh,Jong Heun Lee,Jung Woo Eun,Young-Min Ahn,Su Young Kim,Sug Hyung Lee,Won Sang Park,Nam Jin Yoo,Jung Young Lee,Suk Woo Nam +10 more
TL;DR: Analysis of the expression of HDAC2 in 71 gastric adenocarcinomas by immunohistochemistry suggests thatHDAC2 may play an important role in the aggressiveness of gastric cancer.
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Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b
Jeong Kyu Kim,Ji Heon Noh,Kwang Hwa Jung,Jung Woo Eun,Hyun Jin Bae,Min Gyu Kim,Young Gyoon Chang,Qingyu Shen,Won Sang Park,Jung Young Lee,Jürgen Borlak,Suk Woo Nam +11 more
TL;DR: It is shown that Sirtuin7 expression was up‐regulated in a large cohort of human hepatocellular carcinoma (HCC) patients and a regulatory loop is proposed whereby SIRT7 inhibits transcriptional activation of p21WAF1/Cip1 by way of repression of miR‐125a‐5p and miR-125b.
Journal Article
Somatic Mutations in the Kinase Domain of the Met/Hepatocyte Growth Factor Receptor Gene in Childhood Hepatocellular Carcinomas
Won Sang Park,Seung Myung Dong,Su Young Kim,Eun Young Na,Min Sun Shin,Jae Ho Pi,Bum Jun Kim,Jeong Hoon Bae,Young Ki Hong,Kyo Sun Lee,Sug Hyung Lee,Nam Jin Yoo,Ja June Jang,Svetlana Pack,Zhengping Zhuang,Laura S. Schmidt,Berton Zbar,Jung Young Lee +17 more
TL;DR: The results indicate that mutations of the tyrosine kinase domain of the MET gene may be involved in the acceleration of the carcinogenesis in childhood HCC.
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Somatic Mutations of EGFR Gene in Squamous Cell Carcinoma of the Head and Neck
Jong Woo Lee,Young Hwa Soung,Su Young Kim,Hyo Kyung Nam,Won Sang Park,Suk Woo Nam,Min-Sik Kim,Dong Il Sun,Youn Soo Lee,Ja June Jang,Jung Young Lee,Nam Jin Yoo,Sug Hyung Lee +12 more
TL;DR: It is indicated that in addition to non–small-cell lung cancer, SCCHN harbors the EGFR gene mutations, and the rationale for the clinical applicability of gefinitib toSCCHN patients is suggested.