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Nam Jin Yoo
Researcher at Catholic University of Korea
Publications - 405
Citations - 13537
Nam Jin Yoo is an academic researcher from Catholic University of Korea. The author has contributed to research in topics: Frameshift mutation & Germline mutation. The author has an hindex of 63, co-authored 403 publications receiving 12692 citations. Previous affiliations of Nam Jin Yoo include Catholic University College, Kensington & The Catholic University of America.
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Journal ArticleDOI
Inactivating mutations of the caspase-10 gene in gastric cancer.
Won Sang Park,Jong Heun Lee,Min Sun Shin,Jik Young Park,Hong Sug Kim,Jong Ho Lee,Young Sil Kim,Shi Nae Lee,Wenhua Xiao,Cho Hyun Park,Sug Hyung Lee,Nam Jin Yoo,Jung Young Lee +12 more
TL;DR: The data presented here suggest that somatic alterations of the caspase-10 gene might contribute to the pathogenesis in a subset of gastric cancers through the loss of their apoptotic function.
Journal Article
Frequent Somatic Mutations in Serine/Threonine Kinase 11/Peutz-Jeghers Syndrome Gene in Left-sided Colon Cancer
Seung Myung Dong,Kwangmeyung Kim,Sung-Moo Kim,Myung-Hee Shin,Eun Young Na,Sug Hyung Lee,Weon Seo Park,Nam Jin Yoo,Ja June Jang,C Y Yoon,Jin Woo Kim,Y M Yang,S. H. Kim,Choo Soung Kim,Ji-Yeon Lee +14 more
TL;DR: The results indicate that STK 11 is a tumor suppressor gene and that genetic changes of STK11 play an important role in left-sided colon cancer carcinogenesis.
Journal ArticleDOI
Genetic and expressional alterations of CHD genes in gastric and colorectal cancers
TL;DR: Genetic and expressional alterations of CHD genes in gastric and colorectal cancers and the role of EMTs in these cancers is investigated.
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Somatic mutations of Fas (Apo-1/CD95) gene in cutaneous squamous cell carcinoma arising from a burn scar.
Sug Hyung Lee,Min Sun Shin,Hong Sug Kim,Won Sang Park,Su Young Kim,Ja June Jang,Kyung Jin Rhim,Jin Jang,Hun Kyung Lee,Jik Young Park,Ro Ra Oh,Seo Young Han,Jong Heun Lee,Jung Young Lee,Nam Jin Yoo +14 more
TL;DR: The data show that some burn scar-related squamous cell carcinomas have Fas gene mutations in important regions for the apoptosis function and suggest that these mutations might be involved in the pathogenesis of burn scarThe results provide an important clue to understanding the difference between burn scar and conventional squamouscell carcinoma at the molecular level.
Journal ArticleDOI
Non-small cell lung cancers frequently express phosphorylated Akt; an immunohistochemical study.
Sug Hyung Lee,Hong Sug Kim,Won Sang Park,Su Young Kim,Kyo Young Lee,Sang Ho Kim,Jung Young Lee,Nam Jin Yoo +7 more
TL;DR: The results indicate that Akt 1 is frequently activated in NSCLCs, irrespective of the histological subtypes, and suggest that phosphorylated Akt may play a role in the development of NSCLC rather than in the progression ofNSCLC.