Hormones, antibiotics, vitamins and several other chemicals have been tested in aquaculture operations for various remedies Even though they give positive effects, they cannot be recommended due to their residual and other side effects The alternative herbal bio-medicinal products in the aquacultural operations, that have the characteristics of growth promoting ability and tonic to improve the immune system, act as appetite stimulators They increase consumption, induce maturation, and have antimicrobial capability and also antistress characteristics that will be of immense use in the culture of shrimps and other fin fishes without any environmental and hazardous problems Herbal compounds such as phenolics, polyphenols, alkaloids, quinones, terpenoids, lectines and polypeptides have been shown to be very effective alternatives to antibiotics and other synthetic compounds The present paper is presented after a careful review of more than 50 herbal plants for their biological effects such as growth promotion, immunostimulation, antistress, antibacterial, antifungal, antivirals, appetite stimulators and aphrodisiac

Herbal biomedicines: a new opportunity for aquaculture industry

Impact of plant products on innate and adaptive immune system of cultured finfish and shellfish

The use of medicinal plants as immunostimulants in aquaculture: A review

Beta-glucans as conductors of immune symphonies.

Abstrcat Immunostimulants are valuable for the prevention and control of fish diseases in aquaculture.Several immunostimulants such as polysaccharide and micronutritional factors and their effective mechanism are reviewed, meantime, existing problems in immunostimulant application and future research tendency are described.

Current Research Status of Fish Immunostimulants

Influence of selected Indian immunostimulant herbs against white spot syndrome virus (WSSV) infection in black tiger shrimp, Penaeus monodon with reference to haematological, biochemical and immunological changes.

DNA vaccines encoding viral envelope proteins confer protective immunity against WSSV in black tiger shrimp.

Transcriptional and translational expression profile of a white spot syndrome viral (WSSV) gene in different organs of infected shrimp

Although most SARS-CoV-2 infections are mild, some patients develop systemic inflammation and progress to acute respiratory distress syndrome (ARDS). However, the cellular mechanisms underlying this spectrum of disease remain unclear. γδT cells are T lymphocyte subsets that have key roles in systemic and mucosal immune responses during infection and inflammation. Here we show that peripheral γδT cells are rapidly activated following aerosol or intra-tracheal/intra-nasal (IT/IN) SARS-CoV-2 infection in nonhuman primates. Our results demonstrate a rapid expansion of Vδ1 γδT cells at day1 that correlate significantly with lung viral loads during the first week of infection. Furthermore, increase in levels of CCR6 and Granzyme B expression in Vδ1 T cells during viral clearance imply a role in innate-like epithelial barrier-protective and cytotoxic functions. Importantly, the early activation and mobilization of circulating HLA-DR+CXCR3+ γδT cells along with significant correlations of Vδ1 T cells with IL-1Ra and SCF levels in bronchoalveolar lavage suggest a novel role for Vδ1 T cells in regulating lung inflammation during aerosol SARS-CoV-2 infection. A deeper understanding of the immunoregulatory functions of MHC-unrestricted Vδ1 T cells in lungs during early SARS-CoV-2 infection is particularly important in the wake of emerging new variants with increased transmissibility and immune evasion potential. 

/pdf/the-dynamics-of-gd-t-cell-responses-in-nonhuman-primates-2uthaw30.pdf

The dynamics of γδ T cell responses in nonhuman primates during SARS-CoV-2 infection

http://www.cell.com/article/S2589004222001596/pdf

Namita Rout

Papers

Influence of selected Indian immunostimulant herbs against white spot syndrome virus (WSSV) infection in black tiger shrimp, Penaeus monodon with reference to haematological, biochemical and immunological changes.

DNA vaccines encoding viral envelope proteins confer protective immunity against WSSV in black tiger shrimp.

Transcriptional and translational expression profile of a white spot syndrome viral (WSSV) gene in different organs of infected shrimp

The dynamics of γδ T cell responses in nonhuman primates during SARS-CoV-2 infection

Immunomodulatory potential of in vivo natural killer T (NKT) activation by NKTT320 in Mauritian-origin cynomolgus macaques