K
Kasi E. Russell-Lodrigue
Researcher at Tulane University
Publications - 72
Citations - 2555
Kasi E. Russell-Lodrigue is an academic researcher from Tulane University. The author has contributed to research in topics: Immune system & Medicine. The author has an hindex of 24, co-authored 59 publications receiving 1720 citations. Previous affiliations of Kasi E. Russell-Lodrigue include Texas A&M University & Texas A&M University System.
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Journal ArticleDOI
Adjuvanting a subunit COVID-19 vaccine to induce protective immunity.
Prabhu S. Arunachalam,Alexandra C. Walls,Nadia A. Golden,Caroline Atyeo,Stephanie Fischinger,Chunfeng Li,Pyone P. Aye,Mary Jane Navarro,Lilin Lai,Venkata Viswanadh Edara,Katharina Röltgen,Kenneth A. Rogers,Lisa Shirreff,Douglas E. Ferrell,Samuel Wrenn,Deleah Pettie,John C. Kraft,Marcos C. Miranda,Elizabeth Kepl,Claire Sydeman,Natalie Brunette,Michael E. P. Murphy,Brooke Fiala,Lauren Carter,Alexander G. White,Meera Trisal,Ching-Lin Hsieh,Kasi E. Russell-Lodrigue,Christopher Monjure,Jason Dufour,Skye Spencer,Lara A. Doyle-Meyers,Rudolph Bohm,Nicholas J. Maness,Chad J. Roy,Jessica A. Plante,Kenneth S. Plante,Alex Lee Zhu,Matthew J. Gorman,Sally Shin,Xiaoying Shen,Jane Fontenot,Shakti Gupta,Derek T. O'Hagan,Robbert van der Most,Rino Rappuoli,Robert L. Coffman,David Novack,Jason S. McLellan,Shankar Subramaniam,David C. Montefiori,Scott D. Boyd,JoAnne L. Flynn,Galit Alter,Francois Villinger,Harry Kleanthous,Jay Rappaport,Mehul S. Suthar,Neil P. King,Neil P. King,David Veesler,Bali Pulendran +61 more
TL;DR: In this article, the authors demonstrate the capacity of a subunit vaccine, comprising the SARS-CoV-2 spike protein receptor-binding domain displayed on an I53-50 protein nanoparticle scaffold (hereafter designated RBD-NP), to stimulate robust and durable neutralizing-antibody responses.
Journal ArticleDOI
Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis.
Deepak Kaushal,Taylor W. Foreman,Uma S. Gautam,Xavier Alvarez,Toidi Adekambi,Toidi Adekambi,Javier Rangel-Moreno,Nadia A. Golden,Ann-Marie Johnson,Bonnie L. Phillips,Muhammad H. Ahsan,Kasi E. Russell-Lodrigue,Lara A. Doyle,Chad J. Roy,Peter J. Didier,James Blanchard,Jyothi Rengarajan,Jyothi Rengarajan,Andrew A. Lackner,Shabaana A. Khader,Smriti Mehra,Smriti Mehra +21 more
TL;DR: It is shown that aerosol immunization of macaques with the Mtb mutant in SigH (MtbΔsigH) results in significant recruitment of inducible bronchus-associated lymphoid tissue (iBALT) as well as CD4+ and CD8+ T cells expressing activation and proliferation markers to the lungs.
Journal ArticleDOI
Long-Acting Integrase Inhibitor Protects Macaques from Intrarectal Simian/Human Immunodeficiency Virus
Chasity D. Andrews,William Spreen,Hiroshi Mohri,Lee Moss,Susan L. Ford,Agegnehu Gettie,Kasi E. Russell-Lodrigue,Rudolf P. Bohm,Cecilia Cheng-Mayer,Zhi Hong,Martin Markowitz,David D. Ho +11 more
TL;DR: The results suggest that GSK744 LA could potentially decrease adherence problems associated with daily preexposure prophylaxis (PrEP), and the drug levels required for a high degree of protection could potentially be achieved with quarterly injections in humans.
Journal ArticleDOI
T cells are essential for bacterial clearance, and gamma interferon, tumor necrosis factor alpha, and B cells are crucial for disease development in Coxiella burnetii infection in mice.
Masako Andoh,Guoquan Zhang,Kasi E. Russell-Lodrigue,Heather R. Shive,Brad R. Weeks,James E. Samuel +5 more
TL;DR: The results suggest that T cells are critical for clearance of C. burnetii, either NM I or NM II, that IFN-γ and TNF-α are essential for the early control of infection, and that B cells are important for the prevention of tissue damage.
Journal ArticleDOI
The DosR Regulon Modulates Adaptive Immunity and Is Essential for Mycobacterium tuberculosis Persistence
Smriti Mehra,Taylor W. Foreman,Peter J. Didier,Muhammad H. Ahsan,Teresa A. Hudock,Ryan S. Kissee,Nadia A. Golden,Uma S. Gautam,Ann-Marie Johnson,Xavier Alvarez,Kasi E. Russell-Lodrigue,Lara A. Doyle,Chad J. Roy,Tianhua Niu,James Blanchard,Shabaana A. Khader,Andrew A. Lackner,David R. Sherman,Deepak Kaushal +18 more
TL;DR: The DosR regulon modulates both the magnitude and the timing of adaptive immune responses in response to hypoxia in vivo, resulting in persistent infection and interference with the development of effective antituberculosis vaccines.