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Nan Chen
Researcher at Chinese Academy of Sciences
Publications - 65
Citations - 5366
Nan Chen is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Nanocarriers & Autophagy. The author has an hindex of 29, co-authored 61 publications receiving 4524 citations. Previous affiliations of Nan Chen include Institute of Molecular and Cell Biology & Agency for Science, Technology and Research.
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Protein corona-mediated mitigation of cytotoxicity of graphene oxide
TL;DR: The observation of this FBS-mitigated GO cytotoxicity effect may provide an alternative and convenient route to engineer nanomaterials for safe biomedical and environmental applications.
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Self-Assembled Multivalent DNA Nanostructures for Noninvasive Intracellular Delivery of Immunostimulatory CpG Oligonucleotides
TL;DR: Functional, multivalent DNA nanostructures are developed by appending unmethylated CpG motifs to three-dimensional DNA tetrahedra that are compact, mechanically stable, and noncytotoxic and expected to become a promising tool for targeted drug delivery.
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The cytotoxicity of cadmium-based quantum dots
Nan Chen,Yao He,Yuanyuan Su,Yuanyuan Su,Xiaoming Li,Qing Huang,Haifeng Wang,Xiangzhi Zhang,Renzhong Tai,Chunhai Fan +9 more
TL;DR: Recent progress on mechanistic studies of cytotoxicity of II-IV QDs are summarized to suggest that the cytot toxicity of CdTe QDs not only comes from the release of C d(2+) ions but also intracellular distribution of QD nanoparticles in cells and the associated nanoscale effects.
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Designed Diblock Oligonucleotide for the Synthesis of Spatially Isolated and Highly Hybridizable Functionalization of DNA-Gold Nanoparticle Nanoconjugates
TL;DR: A novel strategy for spatially controlled functionalization of AuNPs with designed diblock oligonucleotides that are free of modifications is reported, which results in DNA-AuNPs nanoconjugates with high and tunable hybridization ability, which form the basis of a rapid plasmonic DNA sensor.
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The biocompatibility of nanodiamonds and their application in drug delivery systems.
Ying Zhu,Jing Li,Wenxin Li,Yu Zhang,Xiafeng Yang,Nan Chen,Yanhong Sun,Yun Zhao,Chunhai Fan,Qing Huang +9 more
TL;DR: An adsorption model for a variety of functional molecules on the ND clusters is proposed, which provides new ideas for developing a novel smart drug with various features such as sustained-release, targeting, and fluorescence imaging.