Nandini Asokan

TL;DR: Designing radioactive bisphosphonate-functionalized platinum ( 195m Pt-BP) complexes to confirm preferential accumulation of these Pt-based drugs in metabolically active bone revealed that release of Pt from Pt BP complexes increased with decreasing pH, and laser ablation-ICP-MS imaging of proximal tibia sections confirmed that195m Pt BP co-localized with calcium in the trabeculae of mice tibia.

TL;DR: In this paper, a transparent embryonic zebrafish xenograft model (eZXM) was used to visualize and track metastatic cells in real time using selective plane illumination microscopy (SPIM) for up to 30h.

TL;DR: The journey of extracellular vesicles from the primary tumor to the future metastatic organ, with a focus on the mechanisms used by EVs to target organs with a specific tropism (i.e., organotropism), and the formation of a pro‐inflammatory and immuno‐tolerant microenvironment is described.

TL;DR: In this paper, an activin receptor type IIB ligand trap was used to restore the ineffective late-stage erythropoiesis of myelodysplastic syndromes (MDS).

TL;DR: It is shown that the capacity of drug-loaded nanoparticles stabilized with citrate ions reduce cancer cell survival in an embryonic zebrafish xenograft model, and that PtPP-loaded HA nanoparticles exhibit anti-proliferative activity against breast cancer cells at reduced pH.