N
Nariman F. Salakhutdinov
Researcher at Russian Academy of Sciences
Publications - 394
Citations - 4121
Nariman F. Salakhutdinov is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 27, co-authored 340 publications receiving 3036 citations. Previous affiliations of Nariman F. Salakhutdinov include Novosibirsk State University.
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Anti-viral activity of (-)- and (+)-usnic acids and their derivatives against influenza virus A(H1N1)2009.
Dmitriy N. Sokolov,Vladimir V. Zarubaev,Anna A. Shtro,Marina P. Polovinka,Olga A. Luzina,Nina I. Komarova,Nariman F. Salakhutdinov,Oleg I. Kiselev +7 more
TL;DR: In this article, the antiviral activity of usnic acid and its derivatives against the pandemic influenza virus A(H1N1)pdm09 was studied for the first time, and a total of 26 compounds representing (+) and (-) isomers of usnik acid and their derivates were tested for cytotoxicity and anti-viral activity in MDCK cells by microtetrazolium test and virus yield assay, respectively.
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Discovery of a new class of antiviral compounds: camphor imine derivatives.
A. S. Sokolova,Olga I. Yarovaya,Olga I. Yarovaya,Andrey V. Shernyukov,Yuriy V. Gatilov,Yuliya V. Razumova,Vladimir V. Zarubaev,Tatiana S. Tretiak,Andrey G. Pokrovsky,Oleg I. Kiselev,Nariman F. Salakhutdinov +10 more
TL;DR: A new class of compounds featuring a camphor moiety that exhibits potent inhibitory activity against influenza A (H1N1)pdm09 and A(H5N1), and the most potent antiviral compound is imine 2 with therapeutic index more than 500.
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Synthesis and biological evaluation of novel tyrosyl-DNA phosphodiesterase 1 inhibitors with a benzopentathiepine moiety.
Alexandra L. Zakharenko,T. M. Khomenko,T. M. Khomenko,Svetlana Zhukova,Olga A. Koval,Olga A. Koval,Olga D. Zakharova,Rashid O. Anarbaev,Rashid O. Anarbaev,Natalya Sh. Lebedeva,Natalya Sh. Lebedeva,Dina V. Korchagina,Nina I. Komarova,Vladimir Vasiliev,Jóhannes Reynisson,Konstantin P. Volcho,Konstantin P. Volcho,Nariman F. Salakhutdinov,Nariman F. Salakhutdinov,Olga I. Lavrik,Olga I. Lavrik +20 more
TL;DR: The study of cytotoxicity of these compounds revealed that all compounds cause an apoptotic cell death in MCF-7 and Hep G2 cells, therefore the new class of very effective inhibitors of TDP1 was elaborated.
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Monoterpenes as a renewable source of biologically active compounds
TL;DR: In this article, a review of various types of biological activity exhibited by monoterpenes and their derivatives, including analgesic, anti-inflammatory, anticonvulsant, antidepressant and anti-Alzheimer, antiParkinsonian, antiviral, and antibacterial (anti-tuberculosis) effects is presented.
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Anti-arthritic agents: Progress and potential ☆
TL;DR: There is an urgent need for further development of better anti-arthritic agents in studies of various agents against osteoarthritis and rheumatoid arthritis.