N
Natalia Danilovich
Researcher at McGill University
Publications - 22
Citations - 1284
Natalia Danilovich is an academic researcher from McGill University. The author has contributed to research in topics: Follicle-stimulating hormone receptor & Estrogen. The author has an hindex of 17, co-authored 22 publications receiving 1236 citations. Previous affiliations of Natalia Danilovich include Southern Illinois University Carbondale & Université de Montréal.
Papers
More filters
Journal ArticleDOI
Estrogen deficiency, obesity, and skeletal abnormalities in follicle-stimulating hormone receptor knockout (FORKO) female mice.
Natalia Danilovich,P. Suresh Babu,Weirong Xing,Maria Gerdes,Hanumanthappa Krishnamurthy,M. Ram Sairam +5 more
TL;DR: The phenotypes evident in these genetically altered FSH-R mutants may provide an experimental system to explore the effects of estrogenic compounds on different targets including the ovary in a nonsurgical setting.
Journal ArticleDOI
Qualitative and Quantitative Decline in Spermatogenesis of the Follicle-Stimulating Hormone Receptor Knockout (FORKO) Mouse
TL;DR: The data allow us to conclude that genetic disruption of FSH receptor signaling in the rodent induces major changes that might contribute to reduced fertility, and sperm from FORKO males are susceptible to acid denaturation, indicating the poor quality of sperm.
Journal ArticleDOI
Deficits in female reproductive function in GH-R-KO mice; role of IGF-I.
TL;DR: It is concluded that GH resistance and consequent reduction in peripheral IGF-I levels is associated with delay of female puberty, alterations in fetal and placental growth, delay of parturition, and reduced litter size.
Journal ArticleDOI
Effects of growth hormone overexpression and growth hormone resistance on neuroendocrine and reproductive functions in transgenic and knock-out mice.
Andrzej Bartke,Varadaraj Chandrashekar,Daniel Turyn,R. W. Steger,Luciano Debeljuk,Todd A. Winters,Julie A. Mattison,Natalia Danilovich,William Croson,Danyel R. Wernsing,John J. Kopchick +10 more
TL;DR: Evidence is provided that GH-transgenic mice have increased binding of GH to GH binding proteins in plasma, are hyperinsulinemic and insulin resistant, and have major alterations in energy budgets with increased allocation to growth.
Journal ArticleDOI
Ovarian pathology and high incidence of sex cord tumors in follitropin receptor knockout (FORKO) mice.
TL;DR: It is proposed that the loss of the FSH receptor signaling mechanisms predispose the ovary to molecular and structural changes leading to tumor formation in the intact and fertile animal, F SH receptor signaling offers a protective mechanism that is lost upon reproductive senescence (menopause in women).