Natalia de las Heras

TL;DR: The potential role of remodeling in the pathogenesis of endorgan damage and in the perpetuation of hypertension is considered, with relatively more weight given to human data in comparison with animal data.

TL;DR: The present review will emphasize the molecular mechanisms underlying the effects of statins on endothelial function and oxidative stress, and inhibition of small GTP-binding proteins, Rho, Ras and Rac, seems to play an important role in mediating the pleiotropic effects ofstatins.

TL;DR: It is indicated that multiple myeloma patients with long-term disease control have a constellation of unique immune changes favoring both immune cytotoxicity and recovery of B-cell production and homing, suggesting improved immune surveillance.

TL;DR: Modifications of mitochondrial dynamics in organs involved in energy metabolism such as the pancreas, liver, skeletal muscle, and white adipose tissue could be of relevance for the development of insulin resistance, obesity, and type 2 diabetes.

TL;DR: The role of angiotensin II in vascular and circulating inflammatory markers in spontaneously hypertensive rats (SHR) is investigated and IL-1β, IL-6, and TNF-α aortic mRNA expression and plasma levels are studied.