V
Victoria Cachofeiro
Researcher at Complutense University of Madrid
Publications - 169
Citations - 5971
Victoria Cachofeiro is an academic researcher from Complutense University of Madrid. The author has contributed to research in topics: Angiotensin II & Oxidative stress. The author has an hindex of 40, co-authored 163 publications receiving 5249 citations. Previous affiliations of Victoria Cachofeiro include Carlos III Health Institute & Hospital General Universitario Gregorio Marañón.
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Journal ArticleDOI
Oxidative stress and inflammation, a link between chronic kidney disease and cardiovascular disease.
Victoria Cachofeiro,Marian Goicochea,Soledad García de Vinuesa,Pilar Oubiña,Vicente Lahera,José Luño +5 more
TL;DR: Statin administration is accompanied by risk reduction in all major vascular events in patients with CKD that are considered high-risk patients, and beneficial effects seem to be consequence of not only their hypolipidemic effect but especially their pleitropic actions that involve modulation of oxidative stress and inflammation.
Journal ArticleDOI
Galectin-3 Mediates Aldosterone-Induced Vascular Fibrosis
Laurent Calvier,María Miana,Pascal Reboul,Victoria Cachofeiro,Ernesto Martínez-Martínez,Rudolf A. de Boer,Françoise Poirier,Patrick Lacolley,Faiez Zannad,Faiez Zannad,Patrick Rossignol,Natalia López-Andrés +11 more
TL;DR: The data indicate that Gal-3 is required for inflammatory and fibrotic responses to Aldo in vascular smooth muscle cells in vitro and in vivo, suggesting a key role forGal-3 in vascular fibrosis.
Journal ArticleDOI
The Impact of Galectin-3 Inhibition on Aldosterone-Induced Cardiac and Renal Injuries
Laurent Calvier,Ernesto Martínez-Martínez,María Miana,Victoria Cachofeiro,Elodie Rousseau,J. Rafael Sadaba,Faiez Zannad,Patrick Rossignol,Natalia López-Andrés,Natalia López-Andrés +9 more
TL;DR: A key role is suggested for Gal-3 in cardiorenal remodeling and dysfunction induced by aldosterone, which could be used as a new biotarget for specific pharmacological interventions.
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Endothelial Dysfunction, Oxidative Stress and Inflammation in Atherosclerosis: Beneficial Effects of Statins
Vicente Lahera,Marian Goicoechea,Soledad García de Vinuesa,María Miana,Natalia de las Heras,Victoria Cachofeiro,José Luño +6 more
TL;DR: The present review will emphasize the molecular mechanisms underlying the effects of statins on endothelial function and oxidative stress, and inhibition of small GTP-binding proteins, Rho, Ras and Rac, seems to play an important role in mediating the pleiotropic effects ofstatins.
Journal ArticleDOI
Low mercury concentrations cause oxidative stress and endothelial dysfunction in conductance and resistance arteries.
Giulia Alessandra Wiggers,Franck Maciel Peçanha,Ana M. Briones,Jose V. Pérez-Girón,Marta Miguel,Dalton Valentim Vassallo,Victoria Cachofeiro,María J. Alonso,Mercedes Salaices +8 more
TL;DR: Chronic exposure to low concentrations of mercury promotes endothelial dysfunction as a result of the decreased NO bioavailability induced by increases in oxidative stress, and offers further evidence that mercury, even at low concentrations, is an environmental risk factor for cardiovascular disease.