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Natalia M. Rodriguez

Researcher at Purdue University

Publications -  49
Citations -  1913

Natalia M. Rodriguez is an academic researcher from Purdue University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 14, co-authored 34 publications receiving 1396 citations. Previous affiliations of Natalia M. Rodriguez include Massachusetts Institute of Technology & Wyss Institute for Biologically Inspired Engineering.

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Alleviating the access abyss in palliative care and pain relief—an imperative of universal health coverage: the Lancet Commission report

TL;DR: The aim of this study was to provide evidence that palliative care and pain relief research should be considered as a continuum of treatment for patients with life-threatening illnesses.
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A fully integrated paperfluidic molecular diagnostic chip for the extraction, amplification, and detection of nucleic acids from clinical samples

TL;DR: The functionality of the chip is showcased by combining nucleic acid isolation, isothermal amplification, and lateral flow detection of human papillomavirus (HPV) 16 DNA directly from crude cervical specimens in less than 1 hour for rapid, early detection of cervical cancer.
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Paper-Based RNA Extraction, in Situ Isothermal Amplification, and Lateral Flow Detection for Low-Cost, Rapid Diagnosis of Influenza A (H1N1) from Clinical Specimens

TL;DR: A paper-based assay that allows for the extraction and purification of RNA directly from human clinical nasopharyngeal specimens through a poly(ether sulfone) paper matrix, H1N1-specific in situ isothermal amplification directly within the same paper Matrix, and immediate visual detection on lateral flow strips, offering a 10-fold improvement over current rapid immunoassays.
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Release of a model protein from biodegradable self assembled films for surface delivery applications

TL;DR: LbL polyelectrolyte films constructed with the model protein lysozyme and a hydrolytically degradable and biocompatible synthetic polycation are characterized and have promise as a tool for exploring protein modulation of the interaction between implanted surfaces and the cells they contact.
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Characterization of tunable FGF-2 releasing polyelectrolyte multilayers

TL;DR: In this paper, the loading and release of FGF-2 from synthetic hydrolytically degradable multilayer thin films of various architectures is explored; drug loading was tunable using at least three parameters (number of nanolayers, counterpolyanion, and type of degradably polycation) and yielded values of 7-45 ng/cm(2) of fibroblast growth factor 2. Release time varied between 24 h and approximately five days.