N
Nathalie Crokart
Researcher at Université catholique de Louvain
Publications - 16
Citations - 927
Nathalie Crokart is an academic researcher from Université catholique de Louvain. The author has contributed to research in topics: Tumor Oxygenation & Tumor microenvironment. The author has an hindex of 13, co-authored 16 publications receiving 857 citations.
Papers
More filters
Journal ArticleDOI
Targeting of tumor endothelium by RGD-grafted PLGA-nanoparticles loaded with Paclitaxel
Fabienne Danhier,Benoît Vroman,Nathalie Lecouturier,Nathalie Crokart,Vincent Pourcelle,Hélène Freichels,Christine Jérôme,Jacqueline Marchand-Brynaert,Olivier Feron,Véronique Préat +9 more
TL;DR: In vivo, the targeting of anti-cancer drug to tumor endothelium by RGD-labeled NP is a promising approach and is demonstrated to be more effective in vitro and in vivo than taxol.
Journal ArticleDOI
Early reoxygenation in tumors after irradiation: determining factors and consequences for radiotherapy regimens using daily multiple fractions
Nathalie Crokart,Bénédicte F. Jordan,Christine Baudelet,Réginald Ansiaux,Pierre Sonveaux,Vincent Grégoire,Nelson Beghein,Julie DeWever,Caroline Bouzin,Olivier Feron,Bernard Gallez +10 more
TL;DR: It is observed that splitting a treatment of 18 Gy into two fractions separated by 4 h had a greater effect on tumor regrowth delay than when applied as a single dose, and the oxygen effect must be also considered to optimize the treatment strategy.
Journal ArticleDOI
Tumor radiosensitization by antiinflammatory drugs: evidence for a new mechanism involving the oxygen effect.
Nathalie Crokart,Kim Radermacher,Bénédicte F. Jordan,Christine Baudelet,Gregory O. Cron,Vincent Grégoire,Nelson Beghein,Caroline Bouzin,Olivier Feron,Bernard Gallez +9 more
TL;DR: In this article, the effect of four NSAIDs (diclofenac, indomethacin, piroxicam, and NS-398) on tumor oxygenation was studied in murine TLT liver tumors and FSaII fibrosarcomas.
Journal ArticleDOI
The role of vessel maturation and vessel functionality in spontaneous fluctuations of T2*‐weighted GRE signal within tumors
Christine Baudelet,Greg O. Cron,Réginald Ansiaux,Nathalie Crokart,Julie DeWever,Olivier Feron,Bernard Gallez +6 more
TL;DR: It is demonstrated that adequate vessel functionality and advanced vessel maturation could explain at least in part the occurrence of spontaneous T2*w GRE signal fluctuations.
Journal ArticleDOI
Mechanism of reoxygenation after antiangiogenic therapy using SU5416 and its importance for guiding combined antitumor therapy.
Réginald Ansiaux,Christine Baudelet,Bénédicte F. Jordan,Nathalie Crokart,Philippe Martinive,Julie DeWever,Vincent Grégoire,Olivier Feron,Bernard Gallez +8 more
TL;DR: The results show that the long-term inhibition of oxygen consumption is a potential novel target in this class of compounds and found that SU5416 potentiated tumor response to radiotherapy but not to chemotherapy.