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Nathan Mewton
Researcher at Claude Bernard University Lyon 1
Publications - 165
Citations - 7054
Nathan Mewton is an academic researcher from Claude Bernard University Lyon 1. The author has contributed to research in topics: Myocardial infarction & Medicine. The author has an hindex of 28, co-authored 129 publications receiving 5737 citations. Previous affiliations of Nathan Mewton include French Institute of Health and Medical Research & Johns Hopkins University.
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Journal ArticleDOI
Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction
Christophe Piot,Pierre Croisille,P. Staat,Hélène Thibault,Gilles Rioufol,Nathan Mewton,Rachid Elbelghiti,Thien Tri Cung,Eric Bonnefoy,Denis Angoulvant,Christophe Macia,Franck Raczka,Catherine Sportouch,Gérald Gahide,Gérard Finet,Xavier André-Fouët,Didier Revel,Gilbert Kirkorian,Jean-Pierre Monassier,Geneviève Derumeaux,Michel Ovize +20 more
TL;DR: Administration of cyclosporine at the time of reperfusion was associated with a smaller infarct by some measures than that seen with placebo, and these data are preliminary and require confirmation in a larger clinical trial.
Journal ArticleDOI
Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation
Jean-François Obadia,David Messika-Zeitoun,Guillaume Leurent,Bernard Iung,Guillaume Bonnet,Nicolas Piriou,Thierry Lefèvre,Christophe Piot,Frédéric Rouleau,Didier Carrié,Mohammed Nejjari,Patrick Ohlmann,Florence Leclercq,Christophe Saint Etienne,Emmanuel Teiger,Lionel Leroux,Nicole Karam,Nicolas Michel,Martine Gilard,Erwan Donal,Jean-Noël Trochu,B. Cormier,Xavier Armoiry,Florent Boutitie,Delphine Maucort-Boulch,Cécile Barnel,Géraldine Samson,Patrice Guerin,Alec Vahanian,Nathan Mewton +29 more
TL;DR: Among patients with severe secondary mitral regurgitation, the rate of death or unplanned hospitalization for heart failure at 1 year did not differ significantly between patients who underwent percutaneous mitral‐valve repair in addition to receiving medical therapy and those who received medical therapy alone.
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Assessment of Myocardial Fibrosis With Cardiovascular Magnetic Resonance
Nathan Mewton,Chia Ying Liu,Pierre Croisille,David A. Bluemke,David A. Bluemke,Joao A.C. Lima +5 more
TL;DR: Cardiovascular magnetic resonance (CMR) may uniquely characterize the extent of replacement fibrosis and may have prognostic value in various cardiomyopathies.
Journal ArticleDOI
Cyclosporine before PCI in Patients with Acute Myocardial Infarction
Thien-Tri Cung,Olivier Morel,Guillaume Cayla,Gilles Rioufol,David Garcia-Dorado,Denis Angoulvant,Eric Bonnefoy-Cudraz,Patrice Guerin,Meier Elbaz,Nicolas Delarche,Pierre Coste,Gérald Vanzetto,Marc Metge,Jean-François Aupetit,Bernard Jouve,Pascal Motreff,Christophe Tron,Jean-Noël Labèque,Philippe Gabriel Steg,Yves Cottin,Grégoire Rangé,Jérôme Clerc,Marc J. Claeys,P Coussement,Fabrice Prunier,Frédéric Moulin,Olivier Roth,Loic Belle,Philippe Dubois,Paul Barragan,Martine Gilard,Christophe Piot,Patrice Colin,Fabien de Poli,Marie-Claude Morice,Omar Ider,Jean-Luc Dubois-Randé,Thierry Unterseeh,Hervé Le Breton,Thierry Beard,Didier Blanchard,Gilles Grollier,Vincent Malquarti,P. Staat,Arnaud Sudre,Eskil Elmér,Magnus Hansson,Cyrille Bergerot,Inesse Boussaha,Claire Jossan,Geneviève Derumeaux,Nathan Mewton,Michel Ovize +52 more
TL;DR: In patients with anterior STEMI who had been referred for primary PCI, intravenous cyclosporine did not result in better clinical outcomes than those with placebo and did not prevent adverse left ventricular remodeling at 1 year.
Journal ArticleDOI
Administration of Cardiac Stem Cells in Patients With Ischemic Cardiomyopathy: The SCIPIO Trial Surgical Aspects and Interim Analysis of Myocardial Function and Viability by Magnetic Resonance
Atul R. Chugh,Garth M. Beache,John H Loughran,Nathan Mewton,Julius B Elmore,Jan Kajstura,Patroklos Pappas,Antone Tatooles,Marcus F. Stoddard,Joao A.C. Lima,Mark S. Slaughter,Piero Anversa,Roberto Bolli +12 more
TL;DR: Isolation of CSCs from cardiac tissue obtained in the operating room is feasible and does not alter practices during CABG surgery, and interim cardiac magnetic resonance results show that CSC infusion produces a striking improvement in both global and regional LV function, a reduction in infarct size, and an increase in viable tissue that persist at least 1 year and are consistent with cardiac regeneration.