Atul R. Chugh

TL;DR: It is suggested that intracoronary infusion of autologous CSCs is effective in improving LV systolic function and reducing infarct size in patients with heart failure after myocardial infarction, and warrant further, larger, phase 2 studies.

TL;DR: Isolation of CSCs from cardiac tissue obtained in the operating room is feasible and does not alter practices during CABG surgery, and interim cardiac magnetic resonance results show that CSC infusion produces a striking improvement in both global and regional LV function, a reduction in infarct size, and an increase in viable tissue that persist at least 1 year and are consistent with cardiac regeneration.

TL;DR: Regardless of its source, acrolein exposure is associated with platelet activation and suppression of circulating angiogenic cell levels, as well as increased CVD risk.

TL;DR: In this article, the authors evaluated the efficacy and safety of endovascular renal denervation in patients with hypertension resistant to three or more antihypertensive medications including a diuretic.

TL;DR: By using an enzymatic dissociation method, a large number, or higher percentage, of relative pure human CSCs with stable expression of c-kit+ could be obtained from atrial appendage specimens within ∼4 weeks following c-Kit MACS without Lin depletion.