N
Nathan Strick
Researcher at New York Blood Center
Publications - 80
Citations - 4121
Nathan Strick is an academic researcher from New York Blood Center. The author has contributed to research in topics: Hepatitis B virus & Virus. The author has an hindex of 32, co-authored 80 publications receiving 4022 citations.
Papers
More filters
Journal ArticleDOI
Identification and Chemical Synthesis of a Host Cell Receptor Binding Site on Hepatitis B Virus
TL;DR: A synthetic peptide analog is recognized by both cell receptors and anti-HBV antibodies and elicits antibodies reacting with native HBV, and is a promising immunogen expected to elicit protective antibodies based on the concept of the attachment blockade pathway of virus neutralization.
Journal ArticleDOI
HIV-1 inhibition by a peptide
Journal ArticleDOI
Hepatitis B virus contains pre-S gene-encoded domains.
TL;DR: The results presented here provide unambiguous evidence that all three env encoded proteins are present in HBV particles; synthetic peptides corresponding to the gene encoding pre-S are highly immunogenic and can be used in diagnostic tests for detection in human sera of antibodies preferentially recognizing HBV.
Journal ArticleDOI
Identification of N-phenyl-N′-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4
Qian Zhao,Liying Ma,Shibo Jiang,Hong Lu,Shuwen Liu,Yuxian He,Nathan Strick,Nouri Neamati,Asim Kumar Debnath +8 more
TL;DR: Two N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamide analogs are identified as a novel class of human immunodeficiency virus type 1 (HIV-1) entry inhibitors that block the gp120-CD4 interaction, showing potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels.
Journal ArticleDOI
Antibodies to a synthetic peptide from the preS 120–145 region of the hepatitis B virus envelope are virus-neutralizing
A. Robert Neurath,Stephen B. H. Kent,K. Parker,Alfred M. Prince,Alfred M. Prince,Nathan Strick,Betsy Brotman,P. Sproul +7 more
TL;DR: In vitro neutralization of the virus by rabbit antiserum to the peptide was assayed in chimpanzees and the animals did not develop hepatitis B, establishing the role of preS domains in the process of virus neutralization and the potential of synthetic preS analogues for hepatitis B vaccination.