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Neal Nathanson

Researcher at University of Pennsylvania

Publications -  88
Citations -  4426

Neal Nathanson is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Virus & Bunyaviridae. The author has an hindex of 35, co-authored 87 publications receiving 4256 citations. Previous affiliations of Neal Nathanson include University of Iceland & National Institutes of Health.

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An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1.

TL;DR: It is shown that HIV-1 89.6 differs markedly from other macrophage-tropic isolates within the envelope V3 region, which is important in determining cell tropism and cytopathicity.
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From Emergence to Eradication: The Epidemiology of Poliomyelitis Deconstructed

TL;DR: Current challenges to the final eradication of paralytic poliomyelitis include the continued transmission of wild polioviruses in endemic reservoirs, reinfection of polio-free areas, outbreaks due to circulating vaccine-derived poliovIRuses, and persistent excretion of vaccine- derived poliovirus by a few vaccinees with B-cell immunodeficiencies.
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Infection of colonic epithelial cell lines by type 1 human immunodeficiency virus is associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor.

TL;DR: Since GalCer is a major glycolipid in epithelial cells of the small intestine and colon, these results provide a structural basis for the binding of HIV-1 by gastrointestinal epithel cells and the entry of the virus into those cells.
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Infection of monocyte-derived macrophages with human immunodeficiency virus type 1 (HIV-1). Monocyte-tropic and lymphocyte-tropic strains of HIV-1 show distinctive patterns of replication in a panel of cell types.

TL;DR: The use of four different cell types provides a useful biological matrix for distinguishing the tropism of different strains of HIV-1; this matrix yields more information than the infection of any single cell type.
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An epidemiologic and clinical evaluation of guillain-barré syndrome reported in association with the administration of swine influenza vaccines

TL;DR: Computerized summaries of approximately 1,300 cases reported as Guillain-Barré syndrome by state health departments to the Centers for Disease Control during the intensive national surveillance instituted following the swine influenza vaccination program in 1976-1977 became available for further study.