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Neeltje van Doremalen
Researcher at National Institutes of Health
Publications - 88
Citations - 18277
Neeltje van Doremalen is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Middle East respiratory syndrome coronavirus & Medicine. The author has an hindex of 33, co-authored 73 publications receiving 13674 citations. Previous affiliations of Neeltje van Doremalen include Rocky Mountain Laboratories.
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Journal ArticleDOI
Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1.
Neeltje van Doremalen,Trenton Bushmaker,Dylan H. Morris,Myndi G. Holbrook,Amandine Gamble,Brandi N. Williamson,Azaibi Tamin,Jennifer L Harcourt,Natalie J. Thornburg,Susan I. Gerber,James O. Lloyd-Smith,Emmie de Wit,Vincent J. Munster +12 more
TL;DR: Aerosol and Surface Stability of SARS-CoV-2 In this research letter, investigators report on the stability of Sars-CoVs and the viability of the two virus under experimental conditions.
Journal ArticleDOI
SARS and MERS: recent insights into emerging coronaviruses
TL;DR: The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second introduction of a highly pathogenic coronav virus into the human population in the twenty-first century, and the current state of development of measures to combat emerging coronaviruses is discussed.
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A Novel Coronavirus Emerging in China - Key Questions for Impact Assessment.
TL;DR: A Novel Coronavirus Emerging in China A novel coronavirus, designated as 2019-nCoV, emerged in Wuhan, China, at the end of 2019, although many details of the emergence of this virus remain unknown.
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ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques.
Neeltje van Doremalen,Teresa Lambe,Alexandra J. Spencer,Sandra Belij-Rammerstorfer,Jyothi N. Purushotham,Jyothi N. Purushotham,Julia R Port,Victoria A. Avanzato,Trenton Bushmaker,Amy Flaxman,Marta Ulaszewska,Friederike Feldmann,Elizabeth R. Allen,Hannah Sharpe,Jonathan E Schulz,Myndi G. Holbrook,Atsushi Okumura,Kimberly Meade-White,Lizzette Pérez-Pérez,Nick J. Edwards,Daniel B. Wright,Cameron Bissett,Ciaran Gilbride,Brandi N. Williamson,Rebecca Rosenke,Dan Long,Alka Ishwarbhai,Reshma Kailath,Louisa Rose,Susan J. Morris,Claire Powers,Jamie Lovaglio,Patrick W. Hanley,Dana P. Scott,Greg Saturday,Emmie de Wit,Sarah C. Gilbert,Vincent J. Munster +37 more
TL;DR: It is shown that the adenovirus-vector-based vaccine ChAdOx1 nCoV-19, which encodes the spike protein of SARS- CoV-2, is immunogenic in mice and elicites a robust humoral and cell-mediated response.
Journal ArticleDOI
Respiratory disease in rhesus macaques inoculated with SARS-CoV-2.
Vincent J. Munster,Friederike Feldmann,Brandi N. Williamson,Neeltje van Doremalen,Lizzette Pérez-Pérez,Jonathan E Schulz,Kimberly Meade-White,Atsushi Okumura,Julie Callison,Beniah Brumbaugh,Victoria A. Avanzato,Rebecca Rosenke,Patrick W. Hanley,Greg Saturday,Dana P. Scott,Elizabeth R. Fischer,Emmie de Wit +16 more
TL;DR: It is shown that SARS-CoV-2 causes a respiratory disease in rhesus macaques that lasts between 8 and 16 days, which recapitulates the moderate disease that has been observed in the majority of human cases of COVID-19.