N
Neha Sharma
Researcher at Indian Council of Medical Research
Publications - 4
Citations - 54
Neha Sharma is an academic researcher from Indian Council of Medical Research. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 1, co-authored 4 publications receiving 7 citations. Previous affiliations of Neha Sharma include Jamia Hamdard.
Papers
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Journal ArticleDOI
Mycobacterium tuberculosis RipA Dampens TLR4-Mediated Host Protective Response Using a Multi-Pronged Approach Involving Autophagy, Apoptosis, Metabolic Repurposing, and Immune Modulation.
Mohd Shariq,Neha Quadir,Neha Quadir,Neha Sharma,Neha Sharma,Jasdeep Singh,Javaid A. Sheikh,Mohd Khubaib,Seyed E. Hasnain,Seyed E. Hasnain,Seyed E. Hasnain,Nasreen Z. Ehtesham +11 more
TL;DR: RipA (Rv1477), a peptidoglycan hydrolase, has been shown to activate the NFκB signaling pathway and elicits the production of pro-inflammatory cytokines, TNF-α, IL-6, and IL-12, through the activation of an innate immune-receptor, toll-like receptor (TLR)4 as mentioned in this paper.
Journal ArticleDOI
Mycobacterium tuberculosis Protein PE6 (Rv0335c), a Novel TLR4 Agonist, Evokes an Inflammatory Response and Modulates the Cell Death Pathways in Macrophages to Enhance Intracellular Survival.
Neha Sharma,Neha Sharma,Mohd Shariq,Neha Quadir,Neha Quadir,Jasdeep Singh,Javaid A. Sheikh,Seyed E. Hasnain,Seyed E. Hasnain,Nasreen Z. Ehtesham +9 more
TL;DR: In this article, the authors show that PE6 protein (Rv0335c) is a secretory protein effector that interacts with TLR4 on the macrophage cell surface and promotes activation of the canonical NF-B signaling pathway to stimulate secretion of proinflammatory cytokines TNF-α, IL-12, and IL-6.
Journal ArticleDOI
In-silico Designing and Testing of Primers for Sanger Genome Sequencing of Dengue Virus Types of Asian Origin
Joshi A,Annette Angel,Bennet Angel,Bennet Angel,Rajendra Kumar Baharia,Rajendra Kumar Baharia,Suman Rathore,Suman Rathore,Neha Sharma,Karuna Yadav,Sharad Thanvi,Indu Thanvi,Vinod Joshi,Vinod Joshi +13 more
TL;DR: New Dengue virus type-specific primer which may help in characterizing virus specific to Asian origin is reported which highlighted importance of use of primer development algorithm and identified genomic regions which are conservative, yet specific for developing primers to achieve efficiency and specificity during experiments.
Book ChapterDOI
Exploration of the Mycobacterial Proteome in the Pathogenesis of TB: A Perspective
Mohd Shariq,Sheeba Zarin,Nilisha Rastogi,Indu Kumari,Farha Naz,Tarina Sharma,Neha Sharma,Nasreen Z. Ehtesham +7 more
TL;DR: Protein profiling of different strains of mycobacteria, clinically relevant, as well as drug-resistant isolates, has tremendously increased our knowledge in the understanding of disease mechanism as discussed by the authors.