Neha Varghese

TL;DR: The Integrated Microbial Genomes & Microbiomes system v.5.0 has a new and more powerful genome search feature, new statistical tools, and supports metagenome binning.

TL;DR: This work demonstrates that the combination of gANI and the alignment fraction between two genomes accurately reflects their genomic relatedness, and proposes this precise and objective AF,gANI-based species definition: the MiSI (Microbial Species Identifier) method, to be used to address previous inconsistencies in species classification.

TL;DR: Since the last report published in the 2012 NAR Database Issue, IMG’s annotation and data integration pipelines have evolved while new tools have been added for recording and analyzing single cell genomes, RNA Seq and biosynthetic cluster data.

TL;DR: It is shown that Rosetta structure prediction guided by residue-residue contacts inferred from evolutionary information can accurately model proteins that belong to large families and that metagenome sequence data more than triple the number of protein families with sufficient sequences for accurate modeling.

TL;DR: Since the last report published in the 2014 NAR Database Issue, IMG/M's dataset content has tripled in terms of number of datasets and overall protein coding genes, while its analysis tools have been extended to cope with the rapid growth in the number and size of datasets handled by the system.