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Neil S. Greenspan
Researcher at Case Western Reserve University
Publications - 83
Citations - 4030
Neil S. Greenspan is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Antigen & Antibody. The author has an hindex of 31, co-authored 79 publications receiving 3909 citations. Previous affiliations of Neil S. Greenspan include Boston Children's Hospital & University Hospitals of Cleveland.
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Journal ArticleDOI
Defining epitopes: It's not as easy as it seems.
Neil S. Greenspan,Di Cera E +1 more
Journal Article
Pretransplant frequency of donor-specific, IFN-gamma-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes.
Peter S. Heeger,Neil S. Greenspan,Shannon Kuhlenschmidt,Cora Dejelo,Donald E. Hricik,James A. Schulak,Magdalena Tary-Lehmann +6 more
TL;DR: Improved ability to define the strength of the allospecific immune response by enzyme-linked immunospot assay may allow improved pairing of recipients with donors and identification of kidney allograft donor-recipient pairs at high risk for acute rejection, thus permitting targeted interventions aimed at prolonging graft survival.
Journal ArticleDOI
TH1-TH2: a procrustean paradigm.
TL;DR: Although immunologists have found the dichotomous helper T cell subset model a useful construct, it is beginning to show its age and some suggest that proponents of the TH1-TH2 dichotomy are overzealous in making the data conform to the scheme.
Journal ArticleDOI
Enzyme Linked Immunosorbent Spot (ELISPOT) Assay for Interferon‐Gamma Independently Predicts Renal Function in Kidney Transplant Recipients
Donald E. Hricik,Victoria Rodriguez,Jocelyn Riley,Katherine Bryan,Magdalena Tary-Lehmann,Neil S. Greenspan,Cora Dejelo,James A. Schulak,Peter S. Heeger,Peter S. Heeger +9 more
TL;DR: Increased levels of early alloreactivity measured with this ELISPOT assay may serve as a surrogate for chronic allograft dysfunction and show an independent correlation between early cellular allore activity and long‐term renal function.
Journal ArticleDOI
Exploring the basis of peptide-carbohydrate crossreactivity: evidence for discrimination by peptides between closely related anti-carbohydrate antibodies.
Shannon L. Harris,Lisa Craig,Jarnail S. Mehroke,Michael Rashed,Michael B. Zwick,Kelly Kenar,Eric J. Toone,Neil S. Greenspan,France-Isabelle Auzanneau,Jose-R. Marino-Albernas,B. Mario Pinto,Jamie K. Scott +11 more
TL;DR: The peptides appear to be specific for their isolating antibodies and are not recognized by the same mechanism as their carbohydrate counterparts.