N
Nguyen Tran Chinh
Researcher at Ho Chi Minh City Medicine and Pharmacy University
Publications - 47
Citations - 5935
Nguyen Tran Chinh is an academic researcher from Ho Chi Minh City Medicine and Pharmacy University. The author has contributed to research in topics: Typhoid fever & Salmonella typhi. The author has an hindex of 32, co-authored 43 publications receiving 5499 citations. Previous affiliations of Nguyen Tran Chinh include University College London.
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Journal ArticleDOI
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia
Menno D. de Jong,Cameron P. Simmons,Tran Tan Thanh,Vo Minh Hien,Gavin J. D. Smith,Tran Nguyen Bich Chau,Dang Minh Hoang,Nguyen Van Vinh Chau,Truong Huu Khanh,Vo Cong Dong,Phan Tu Qui,Bach Van Cam,Do Quang Ha,Yi Guan,J. S. Malik Peiris,Nguyen Tran Chinh,Tran Tinh Hien,Jeremy Farrar +17 more
TL;DR: The observations indicate that high viral load, and the resulting intense inflammatory responses, are central to influenza H5N1 pathogenesis and the focus of clinical management should be on preventing this intense cytokine response, by early diagnosis and effective antiviral treatment.
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The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis
Maxine Caws,Maxine Caws,Guy E. Thwaites,Sarah J. Dunstan,Sarah J. Dunstan,Thomas R. Hawn,Nguyen Ngoc Lan,Nguyen Thuy Thuong Thuong,Kasia Stepniewska,Mai N. T. Huyen,Nguyen Duc Bang,Tran Huu Loc,Sebastien Gagneux,Dick van Soolingen,Kristin Kremer,Marianne A B van der Sande,Peter M. Small,Peter M. Small,Phan Thi Hoang Anh,Nguyen Tran Chinh,Hoang Thi Quy,Nguyen Thi Hong Duyen,Dau Quang Tho,Nguyen Trong Hieu,Estee Torok,Estee Torok,Tran Tinh Hien,Nguyen Huy Dung,Nguyen Thi Quynh Nhu,Phan Minh Duy,Nguyen Van Vinh Chau,Jeremy Farrar,Jeremy Farrar +32 more
TL;DR: Evidence that M. tuberculosis genotype influences clinical disease phenotype is provided and a significant interaction between host and bacterial genotypes and the development of tuberculosis is demonstrated for the first time.
Journal ArticleDOI
Evolutionary History of Salmonella Typhi
Philippe Roumagnac,François-Xavier Weill,Christiane Dolecek,Stephen Baker,Sylvain Brisse,Nguyen Tran Chinh,Thi Anh Hong Le,Camilo J. Acosta,Jeremy Farrar,Gordon Dougan,Mark Achtman +10 more
TL;DR: The neutral population structure of Salmonella enterica serovar Typhi reflects the continued existence of ubiquitous haplotypes over millennia, and antibiotic-sensitive strains and haplotypes other than H58 still persist despite selection for antibiotic resistance.
Journal ArticleDOI
Streptococcus suis Meningitis in Adults in Vietnam
Nguyen Thi Hoang Mai,Ngo Thi Hoa,Tran Vu Thieu Nga,Le Dieu Linh,Tran Thi Hong Chau,Dinh Xuan Sinh,Nguyen Hoan Phu,Ly Van Chuong,To Song Diep,James Campbell,James Campbell,Ho Dang Trung Nghia,Tran Ngoc Minh,Nguyen Van Vinh Chau,Menno D. de Jong,Menno D. de Jong,Menno D. de Jong,Nguyen Tran Chinh,Tran Tinh Hien,Jeremy Farrar,Jeremy Farrar,Constance Schultsz,Constance Schultsz +22 more
TL;DR: S. suis serotype 2 is the most frequent cause of bacterial meningitis in adults in southern Vietnam and is associated with substantial morbidity attributable to hearing loss.
Journal ArticleDOI
Timing of Initiation of Antiretroviral Therapy in Human Immunodeficiency Virus (HIV)–Associated Tuberculous Meningitis
M. Estée Török,M. Estée Török,Nguyen Thi Yen,Tran Thi Hong Chau,Nguyen Thi Hoang Mai,Nguyen Hoan Phu,Pham Phuong Mai,Nguyen Thi Dung,Nguyen Van Vinh Chau,Nguyen Duc Bang,Nguyen Anh Tien,N. H. Minh,Nguyen Quang Hien,Phan Vuong Khac Thai,Do Thi Tuong Anh,Nguyen Thi Cam Thoa,Nguyen Ngoc Hai,Nguyen Ngoc Lan,Nguyen Thi Ngoc Lan,Hoang Thi Quy,Nguyen Huy Dung,Tran Tinh Hien,Nguyen Tran Chinh,Cameron P. Simmons,Menno de Jong,Menno de Jong,Marcel Wolbers,Jeremy Farrar +27 more
TL;DR: There were significantly more grade 4 adverse events in the immediate ART arm, supporting delayed initiation of ART in HIV-associated tuberculous meningitis.