T
Tran Thi Hong Chau
Researcher at University of Oxford
Publications - 83
Citations - 6804
Tran Thi Hong Chau is an academic researcher from University of Oxford. The author has contributed to research in topics: Tuberculous meningitis & Meningitis. The author has an hindex of 42, co-authored 76 publications receiving 6201 citations. Previous affiliations of Tran Thi Hong Chau include Wellcome Trust & University College London.
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Journal ArticleDOI
Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections
David M. Tobin,Francisco J. Roca,Sungwhan F. Oh,Ross McFarland,Thad Vickery,John P. Ray,Dennis C. Ko,Yuxia Zou,Nguyen Duc Bang,Tran Thi Hong Chau,Jay C. Vary,Thomas R. Hawn,Sarah J. Dunstan,Jeremy Farrar,Guy E. Thwaites,Mary Claire King,Charles N. Serhan,Lalita Ramakrishnan +17 more
TL;DR: It is suggested that host-directed therapies tailored to patient LTA4H genotypes may counter detrimental effects of either extreme of inflammation, and therapies that specifically target each of these extremes are identified.
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The Prognostic and Pathophysiologic Role of Pro- and Antiinflammatory Cytokines in Severe Malaria
Nicholas P. J. Day,Tran Tinh Hien,Tineke Schollaardt,Pham Phu Loc,Ly Van Chuong,Tran Thi Hong Chau,Nguyen Thi Hoang Mai,Nguyen Hoan Phu,Dinh Xuan Sinh,Nicholas J. White,Nicholas J. White,May Ho +11 more
TL;DR: Elevated plasma cytokines in severe malaria are associated with systemic pathologic abnormalities, not cerebral involvement, and both the overall magnitude of the cytokine responses and the eventual imbalance between the pro- and antiinflammatory responses are important determinants of mortality.
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Hemofiltration and peritoneal dialysis in infection-associated acute renal failure in Vietnam.
Nguyen Hoan Phu,Tran Tinh Hien,Nguyen Thi Hoang Mai,Tran Thi Hong Chau,Ly Van Chuong,Pham Phu Loc,Christopher G. Winearls,Jeremy Farrar,Nicholas J. White,Nicholas P. J. Day +9 more
TL;DR: Hemofiltration is superior to peritoneal dialysis in the treatment of infection-associated acute renal failure and the cost per life saved was less than one third.
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Streptococcus suis Meningitis in Adults in Vietnam
Nguyen Thi Hoang Mai,Ngo Thi Hoa,Tran Vu Thieu Nga,Le Dieu Linh,Tran Thi Hong Chau,Dinh Xuan Sinh,Nguyen Hoan Phu,Ly Van Chuong,To Song Diep,James Campbell,James Campbell,Ho Dang Trung Nghia,Tran Ngoc Minh,Nguyen Van Vinh Chau,Menno D. de Jong,Menno D. de Jong,Menno D. de Jong,Nguyen Tran Chinh,Tran Tinh Hien,Jeremy Farrar,Jeremy Farrar,Constance Schultsz,Constance Schultsz +22 more
TL;DR: S. suis serotype 2 is the most frequent cause of bacterial meningitis in adults in southern Vietnam and is associated with substantial morbidity attributable to hearing loss.
Journal ArticleDOI
Timing of Initiation of Antiretroviral Therapy in Human Immunodeficiency Virus (HIV)–Associated Tuberculous Meningitis
M. Estée Török,M. Estée Török,Nguyen Thi Yen,Tran Thi Hong Chau,Nguyen Thi Hoang Mai,Nguyen Hoan Phu,Pham Phuong Mai,Nguyen Thi Dung,Nguyen Van Vinh Chau,Nguyen Duc Bang,Nguyen Anh Tien,N. H. Minh,Nguyen Quang Hien,Phan Vuong Khac Thai,Do Thi Tuong Anh,Nguyen Thi Cam Thoa,Nguyen Ngoc Hai,Nguyen Ngoc Lan,Nguyen Thi Ngoc Lan,Hoang Thi Quy,Nguyen Huy Dung,Tran Tinh Hien,Nguyen Tran Chinh,Cameron P. Simmons,Menno de Jong,Menno de Jong,Marcel Wolbers,Jeremy Farrar +27 more
TL;DR: There were significantly more grade 4 adverse events in the immediate ART arm, supporting delayed initiation of ART in HIV-associated tuberculous meningitis.