N
Nicola H. Green
Researcher at University of Sheffield
Publications - 50
Citations - 1717
Nicola H. Green is an academic researcher from University of Sheffield. The author has contributed to research in topics: Antigen & Chinese hamster ovary cell. The author has an hindex of 18, co-authored 47 publications receiving 1480 citations. Previous affiliations of Nicola H. Green include University College London & University of Nottingham.
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Journal ArticleDOI
Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin.
TL;DR: It is demonstrated that the helper T cell clone can be inhibited by the relevant peptide in the absence of any suppressor cells or their precursors, suggesting that antigen-induced unresponsiveness need not always depend on the presence of suppressor T cells.
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Dinuclear Ruthenium( II) Complexes as Two- Photon, Time- Resolved Emission Microscopy Probes for Cellular DNA
Elizabeth Baggaley,Martin R. Gill,Nicola H. Green,David Turton,Igor V. Sazanovich,Stanley W. Botchway,Carl Smythe,John W. Haycock,Julia A. Weinstein,Jim A. Thomas +9 more
TL;DR: Ruthenium(II) luminophores are used as phosphorescent lifetime imaging microscopy (PLIM) probes for nuclear DNA in both live and fixed cells, leading to previously unattainable levels of sensitivity, and autofluorescence-free imaging.
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Controlled Human Infection and Rechallenge with Streptococcus pneumoniae Reveals the Protective Efficacy of Carriage in Healthy Adults
Daniela M. Ferreira,Daniel R. Neill,Mathieu Bangert,Jenna F. Gritzfeld,Nicola H. Green,Adam K. A. Wright,Shaun H. Pennington,Laura Bricio Moreno,Adriana T. Moreno,Eliane N. Miyaji,Angela D. Wright,Andrea M. Collins,David Goldblatt,Aras Kadioglu,Stephen B. Gordon +14 more
TL;DR: Experimental human carriage resulted in mucosal and systemic immunological responses that conferred protection against recolonization and invasive pneumococcal disease, suggesting that mucosal pneumococCal vaccination strategies may be important for vulnerable patient groups, particularly the elderly, who do not sustain carriage.
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Constraints on the transport and glycosylation of recombinant IFN-gamma in Chinese hamster ovary and insect cells.
Andrew D. Hooker,Nicola H. Green,Anthony J. Baines,Alan T. Bull,Nigel Jenkins,Philip G. Strange,Philip G. Strange,David C. James +7 more
TL;DR: Although the limitations on intracellular transport and secretion of recombinant proteins in mammalian and insect cells are similar, N-glycan processing in Sf insect cells is limited, and that genetic modification of N-behavioural processing in these insect cell lines will be constrained by substrate availability to terminal galactosylation.
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Emulsion templated scaffolds with tunable mechanical properties for bone tissue engineering
Robert Owen,Colin Sherborne,Thomas E. Paterson,Nicola H. Green,Gwendolen C. Reilly,Frederik Claeyssens +5 more
TL;DR: The scaffolds supported osteogenic differentiation of mesenchymal cells and interestingly, the stiffest IBOA-based scaffolds that were plasma treated with acrylic acid promoted osteogenesis more strongly than the other scaffolds.