Nicola Maffulli

TL;DR: The main biological technologies to boost musculoskeletal healing, including bone marrow and subcutaneous fat-derived regenerative products, as well as platelet-rich plasma and conditioned media are described.

TL;DR: No statistical significant differences were found between conservative and surgical approaches in terms of postoperative osteoarthritis and persistence ofPain, although persistence of pain seemed to occur less frequently in patients undergoing a surgical treatment.

TL;DR: The association of arthroscopic implantation of autologous chondrocytes with a medial opening wedge osteotomy of the proximal tibia is a viable option for the management of chondral defects in varus knees.

TL;DR: This article provides a summary of previous work concerning the mechanics of external ring fixators and how they affect the biomechanical environment at the fracture/osteotomy site.

TL;DR: Histological and histomorphometric analysis suggested 1 mm/day to be the ideal distraction rate, as this was associated with greater osteoblastic activity and consistent bony union, but IGF-1 infusion significantly enhanced osteobastic activity at both distraction rates and resulted in bonyunion when distraction was performed at 3 mm/ day.