N
Nicolas Ferry
Researcher at French Institute of Health and Medical Research
Publications - 75
Citations - 2244
Nicolas Ferry is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Transgene & Genetic enhancement. The author has an hindex of 26, co-authored 75 publications receiving 2176 citations. Previous affiliations of Nicolas Ferry include École Normale Supérieure & Pasteur Institute.
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Journal ArticleDOI
Efficient Transfer of Regulated Genes in Adipocytes and Hepatoma Cells by the Combination of Liposomes and Replication‐Deficient Adenovirus
TL;DR: The association of liposomes and adenovirus is an efficient method for transient or stable transfer of regulated genes in adipocytes and hepatoma cells.
Journal ArticleDOI
Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney.
André Pawlak,Shi Jun Wu,Frédérique Bulle,Atsuo Suzuki,Naima Chikhi,Nicolas Ferry,Ja Hyun Baik,S. Siegrist,Georges Guellaen +8 more
TL;DR: The sequencing of a human genomic clone reveals that this type II GGT mRNA is encoded by a different gene than the type I GGT RNA, which is expressed in human liver, while almost exclusively type Two GGTRNA is detected in human kidney.
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Transient expression of genes delivered to newborn rat liver using recombinant adeno-associated virus 2/8 vectors.
Maude Flageul,Dominique Aubert,Virginie Pichard,Tuan Huy Nguyen,Ali Nowrouzi,Manfred Schmidt,Nicolas Ferry +6 more
TL;DR: Transgene expression after AAV8 delivery of a therapeutic or a marker gene to newborn rat liver is analysed and it is suggested that AAV delivery to the newborn liver may result in transient expression.
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Critical assessment of lifelong phenotype correction in hyperbilirubinemic Gunn rats after retroviral mediated gene transfer
Tuan Huy Nguyen,Dominique Aubert,Marta Bellodi-Privato,Maude Flageul,Virginie Pichard,Z Jaidane-Abdelghani,A Myara,Nicolas Ferry +7 more
TL;DR: The present results document the lifelong safety of gene therapy for CN-1 with retroviral vectors and offer a better delineation of liver gene correction level required to achieve complete correction of bilirubinemia and pave the way for future clinical application of gene Therapy for inherited liver disorders.
Journal ArticleDOI
Alloantigen gene transfer to hepatocytes promotes tolerance to pancreatic islet graft by inducing CD8+ regulatory T cells.
Valentin Le Guen,Jean-Paul Judor,Françoise Boeffard,Vanessa Gauttier,Nicolas Ferry,Jean-Paul Soulillou,Sophie Brouard,Sophie Conchon +7 more
TL;DR: It is demonstrated for the first time that the in vivo gene transfer of an allogeneic antigen with an adeno-associated viral vector to mouse hepatocytes induces the expansion of a population of CD8+ regulatory T lymphocytes.