Nicolas Richard

TL;DR: A 11-year-old girl with disease limited to major pulmonary haemosiderosis manifesting at the age of 2 years, due to a heterozygous p.(Arg233His) mutation in COPA was treated with the JAK1/2 inhibitor ruxolitinib, which resulted in reduction in IFN signalling and appeared to be associated with partial though incomplete decrease in the severity of her pulmonary disease.

TL;DR: The youngest patients seem to present milder forms of COVID-19 without the need for ICU treatment and with a shorter length of hospitalization, which suggests intra-familial transmission that needs to be further assessed.

TL;DR: In this article, the role of bronchial epithelial cells, i.e., the BEAS-2B cell line and human primary cells, in conidial germination of a laboratory strain and three clinical strains of Aspergillus fumigatus was investigated.

TL;DR: There is a high prevalence of obstructive sleep apnea (OSA) in children with Down syndrome (DS), sometimes associated with alveolar hypoventilation.

TL;DR: LUS could be an interesting tool for screening and monitoring children with ILD, reducing their exposure to x-rays in comparison to CT, and demonstrated a good correlation between LUS and CT images.