N
Nicolás Villegas-Sepúlveda
Researcher at CINVESTAV
Publications - 57
Citations - 1537
Nicolás Villegas-Sepúlveda is an academic researcher from CINVESTAV. The author has contributed to research in topics: Gene & Dengue virus. The author has an hindex of 19, co-authored 54 publications receiving 1301 citations. Previous affiliations of Nicolás Villegas-Sepúlveda include Instituto Politécnico Nacional.
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Journal ArticleDOI
Single multiplex polymerase chain reaction to detect diverse loci associated with diarrheagenic Escherichia coli.
Catalina Lopez-Saucedo,Jorge F. Cerna,Nicolás Villegas-Sepúlveda,Rocío Thompson,F. Raúl Velázquez,Javier Torres,Phillip I. Tarr,Teresa Estrada-Garcia +7 more
TL;DR: A single multiplex polymerase chain reaction (PCR) is developed that detects enterotoxigenic, enteropathogenic, enteroinvasive, and Shiga-toxin–producing Escherichia coli and warrants further evaluation in large, prospective studies of polymicrobial substances.
Journal ArticleDOI
Translation Elongation Factor-1α, La, and PTB Interact with the 3′ Untranslated Region of Dengue 4 Virus RNA
TL;DR: The specific binding of La and PTB to the sequences considered essential for viral RNA replication may suggest that these proteins could function as RNA chaperones to maintain RNA structure in a conformation that favors viral replication, while EF-1alpha may function as an RNA helicase.
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Recombinant Dengue virus protein NS2B alters membrane permeability in different membrane models.
Moisés León-Juárez,Macario Martínez-Castillo,Gaurav Shrivastava,Julio García-Cordero,Nicolás Villegas-Sepúlveda,Mónica Mondragón-Castelán,Ricardo Mondragón-Flores,Leticia Cedillo-Barrón +7 more
TL;DR: The data suggest that the DENV-2 NS2B viral protein is capable of oligomerizing and organizing to form pore-like structures in different lipid environments, thereby modifying the permeability of cell membranes.
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Two long non-coding RNAs generated from subtelomeric regions accumulate in a novel perinuclear compartment in Plasmodium falciparum.
Miguel Sierra-Miranda,Dulce María Delgadillo,Liliana Mancio-Silva,Liliana Mancio-Silva,Miguel Vargas,Nicolás Villegas-Sepúlveda,Santiago Martínez-Calvillo,Artur Scherf,Artur Scherf,Rosaura Hernández-Rivas +9 more
TL;DR: It is demonstrated that telomere-associated repeat elements (TAREs) and telomeres are transcribed as long non-coding RNAs (lncRNAs) during schizogony and the TARE-6 lncRNA is predicted to form a stable and repetitive hairpin structure that is able to bind histones.
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Molecular characterization of two genes encoding betaine aldehyde dehydrogenase from amaranth. Expression in leaves under short-term exposure to osmotic stress or abscisic acid
J Legaria,Ricardo Rajsbaum,Rosario A. Muñoz-Clares,Nicolás Villegas-Sepúlveda,June Simpson,Gabriel Iturriaga +5 more
TL;DR: Results showed that mRNA and BADH protein are present in non-treated amaranth leaves and both transiently increased under short-term exposure to abscisic acid (ABA) and osmotic stress treatments.