N
Nicole Morel
Researcher at Université catholique de Louvain
Publications - 98
Citations - 2500
Nicole Morel is an academic researcher from Université catholique de Louvain. The author has contributed to research in topics: Voltage-dependent calcium channel & Calcium. The author has an hindex of 29, co-authored 97 publications receiving 2404 citations. Previous affiliations of Nicole Morel include Niigata University & Katholieke Universiteit Leuven.
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AMP-activated protein kinase phosphorylates and desensitizes smooth muscle myosin light chain kinase.
Sandrine Horman,Nicole Morel,Didier Vertommen,Nusrat Hussain,Dietbert Neumann,Christophe Beauloye,Nicole El Najjar,Christelle Forcet,Benoit Viollet,Michael P. Walsh,Louis Hue,Mark H. Rider +11 more
TL;DR: The findings suggest that AMPK attenuates contraction by phosphorylating and inactivating MLCK, a substrate of AMP-activated protein kinase (AMPK), which might contribute to reduced ATP turnover in the tonic phase of smooth muscle contraction.
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Pharmacological evidence of hypotensive activity of Marrubium vulgare and Foeniculum vulgare in spontaneously hypertensive rat.
TL;DR: Results indicate that hypotensive activity of Marrubium and Foeniculum extracts seems to be mediated through different pathways: Foeniulum appeared to act mainly as a diuretic and a natriuretic while Mar rubium displayed vascular relaxant activity.
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The vasorelaxant activity of marrubenol and marrubiin from Marrubium vulgare.
Sanae El Bardai,Nicole Morel,Maurice Wibo,Nicolas Fabre,Gabriel Llabres,Badiaa Lyoussi,Joëlle Quetin-Leclercq +6 more
TL;DR: Crude extracts of the aerial parts of Marrubium vulgare show a potent in vitro inhibition of KCl-induced contraction of rat aorta and furanic labdane diterpenes marrubenol and marrubiin as the most active compounds.
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Rho‐dependent kinase is involved in agonist‐activated calcium entry in rat arteries
TL;DR: Results indicate that Rho‐kinase is involved in noradrenaline activation of a Ca2+ entry distinct from voltage‐ or store‐operated channels in rat arteries.
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The action of calcium channel blockers on recombinant L‐type calcium channel α1‐subunits
TL;DR: Results indicate marked differences among Ca2+ channel blockers in their selectivity for the α1C‐a and α 1C‐b subunits of the Ca2+, and neutral dihydropyridines had a higher affinity for the β‐a than for theβ‐a subunit.