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Nigel J. Fullwood
Researcher at Lancaster University
Publications - 129
Citations - 9804
Nigel J. Fullwood is an academic researcher from Lancaster University. The author has contributed to research in topics: Transplantation & Cornea. The author has an hindex of 46, co-authored 129 publications receiving 8689 citations. Previous affiliations of Nigel J. Fullwood include Open University & University of Sheffield.
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Journal ArticleDOI
Using Fourier transform IR spectroscopy to analyze biological materials
Matthew J. Baker,Júlio Trevisan,Paul Bassan,Rohit Bhargava,Holly J. Butler,Konrad Matthew Dorling,Peter R. Fielden,Simon W. Fogarty,Nigel J. Fullwood,Kelly A. Heys,Caryn Hughes,Peter Lasch,Pierre L. Martin-Hirsch,Blessing Obinaju,Ganesh D. Sockalingum,Josep Sulé-Suso,Rebecca J. Strong,Michael J. Walsh,Bayden R. Wood,Peter Gardner,Francis Martin +20 more
TL;DR: This manuscript brings together some of the leaders in this field to allow the standardization of methods and procedures for adapting a multistage approach to a methodology that can be applied to a variety of cell biological questions or used within a clinical setting for disease screening or diagnosis.
Journal ArticleDOI
Using Raman spectroscopy to characterize biological materials
Holly J. Butler,Lorna Ashton,Benjamin Bird,Gianfelice Cinque,Kelly Curtis,Jennifer Dorney,Karen A. Esmonde-White,Nigel J. Fullwood,Benjamin Gardner,Pierre L. Martin-Hirsch,Pierre L. Martin-Hirsch,Michael J. Walsh,Martin R. McAinsh,Nicholas Stone,Francis Martin +14 more
TL;DR: A robust approach for sample preparation, instrumentation, acquisition parameters and data processing is explored and it is expected that a typical Raman experiment can be performed by a nonspecialist user to generate high-quality data for biological materials analysis.
Journal ArticleDOI
Growth factor mRNA and protein in preserved human amniotic membrane.
Noriko Koizumi,Tsutomu Inatomi,Chie Sotozono,Nigel J. Fullwood,Andrew J. Quantock,Shigeru Kinoshita +5 more
TL;DR: Preserved human AM expresses mRNAs for a number of growth factors and contains several growth factor proteins that might benefit epithelialization after AM transplantation, suggesting an epithelial origin for these growth factors.
Journal ArticleDOI
α-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma
Omar M. A. El-Agnaf,Sultan A. Salem,Katerina E. Paleologou,Leanne J. Cooper,Nigel J. Fullwood,Mark J. Gibson,Martin D. Curran,Jennifer A. Court,David M. A. Mann,Shu-ichi Ikeda,Mark R. Cookson,John Hardy,David Allsop +12 more
TL;DR: The findings suggest that cells normally secrete α‐syn into their surrounding media, both in vitro and in vivo, and the detection of extracellular α‐ syn and/or its modified forms in body fluids, particularly in human plasma, offers new opportunities for the development of diagnostic tests for PD.
Journal ArticleDOI
Amniotic Membrane as a Carrier for Cultivated Human Corneal Endothelial Cell Transplantation
Yutaka Ishino,Yoichiro Sano,Takahiro Nakamura,Che J. Connon,Helen Rigby,Nigel J. Fullwood,Shigeru Kinoshita +6 more
TL;DR: The results indicate that amniotic membrane maintains HCEC morphology and function and could serve as a carrier for cHCEC transplantation, and cHC ECs on AM were functional in vivo.