Nikolaus J. Sucher

TL;DR: The data delineate a mechanistic model of the dynamic regulation of a PP2A–NMDAR signaling complex, mediated by the interaction of NR3A andPP2A, and suggest a novel NMDAR-mediated signaling mechanism in addition to the traditional ionotropic functions of N MDARs.

TL;DR: A novel method for the fast identification of genetic material utilizing a micro-DNA amplification and analysis device (micro-DAAD) consisting of multiple PCR microreactors with integrated DNA microarrays was developed and successful amplification of the genetic material and the consecutive analysis of the fluorescent-labeled amplicons by the integrated oligonucleotide probes were demonstrated.

TL;DR: If therapeutic concentrations can be achieved in target tissues, cinnamon and its components may be useful in the treatment of age-related inflammatory conditions.

TL;DR: Inhibition of the Müller cell KIR channels by the neurotransmitter glutamate is likely to have significant functional consequences for the retina since these ion channels are involved in K+ homeostasis, which in turn influences neuronal excitability.

TL;DR: Steps of a comprehensive quality assurance paradigm aimed at achieving and maintaining safety, consistent phytochemical composition, and clinical efficacy of ingredients of herbal medicines are outlined.