N
Nikolay Vyahhi
Researcher at Saint Petersburg Academic University
Publications - 13
Citations - 22980
Nikolay Vyahhi is an academic researcher from Saint Petersburg Academic University. The author has contributed to research in topics: Computer science & Set (abstract data type). The author has an hindex of 8, co-authored 10 publications receiving 16491 citations. Previous affiliations of Nikolay Vyahhi include Saint Petersburg State University & University of California, San Diego.
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Journal ArticleDOI
SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing
Anton Bankevich,Sergey Nurk,Dmitry Antipov,Alexey Gurevich,Mikhail Dvorkin,Alexander S. Kulikov,Valery M. Lesin,Sergey I. Nikolenko,Son Pham,Andrey D. Prjibelski,Alexey V. Pyshkin,Alexander Sirotkin,Nikolay Vyahhi,Glenn Tesler,Max A. Alekseyev,Pavel A. Pevzner +15 more
TL;DR: SPAdes generates single-cell assemblies, providing information about genomes of uncultivatable bacteria that vastly exceeds what may be obtained via traditional metagenomics studies.
Journal ArticleDOI
QUAST: quality assessment tool for genome assemblies
TL;DR: This tool improves on leading assembly comparison software with new ideas and quality metrics, and can evaluate assemblies both with a reference genome, as well as without a reference.
Journal ArticleDOI
Candidate phylum TM6 genome recovered from a hospital sink biofilm provides genomic insights into this uncultivated phylum
Jeffrey S. McLean,Jeffrey S. McLean,Mary-Jane Lombardo,Jonathan H. Badger,Anna Edlund,Mark Novotny,Joyclyn Yee-Greenbaum,Nikolay Vyahhi,Adam P. Hall,Youngik Yang,Christopher L. Dupont,Michael G. Ziegler,Hamidreza Chitsaz,Andrew E. Allen,Shibu Yooseph,Glenn Tesler,Pavel A. Pevzner,Pavel A. Pevzner,Robert Friedman,Kenneth H. Nealson,Kenneth H. Nealson,J. Craig Venter,Roger S. Lasken +22 more
TL;DR: An approach for increasing throughput and effectively improving the likelihood of sampling rare events based on forming small random pools of single-flow–sorted cells, amplifying their DNA by multiple displacement amplification and sequencing all cells in the pool, creating a “mini-metagenome” is developed.
Book ChapterDOI
Sibelia: A Scalable and Comprehensive Synteny Block Generation Tool for Closely Related Microbial Genomes
Ilya Minkin,Ilya Minkin,Anand Patel,Anand Patel,Mikhail Kolmogorov,Mikhail Kolmogorov,Nikolay Vyahhi,Nikolay Vyahhi,Son Pham,Son Pham +9 more
TL;DR: Sibelia is a tool for finding synteny blocks in multiple closely related microbial genomes using iterative de Bruijn graphs that can find synteny Blocks that are repeated within genomes as well as blocks shared by multiple genomes.
Journal ArticleDOI
C-Sibelia: an easy-to-use and highly accurate tool for bacterial genome comparison
TL;DR: C-Sibelia is a highly accurate and easy-to-use software tool for comparing two closely related bacterial genomes, which can be presented as either finished sequences or fragmented assemblies.