Anna Edlund

TL;DR: In GNPS, crowdsourced curation of freely available community-wide reference MS libraries will underpin improved annotations and data-driven social-networking should facilitate identification of spectra and foster collaborations.

TL;DR: The notion of “reference frames” is defined, which provide deep intuition about the compositional nature of microbiome data, which allow reassessment of published relative abundance data to reveal reproducible microbial changes from standard sequencing output without the need for new assays.

TL;DR: This first completed genome for a human-associated TM7 phylotype revealed a complete lack of amino acid biosynthetic capacity, and comparative genomics analyses with uncultivated environmental TM7 assemblies show remarkable conserved gene synteny and only minimal gene loss/gain that may have occurred as TM7x adapted to conditions within the human host.

TL;DR: A novel genetic risk score for β-cell dysfunction is created that includes aberrant granule docking, decreased Ca2+ sensitivity of exocytosis, and reduced insulin release in type 2 diabetes patients with a high risk score.

TL;DR: An approach for increasing throughput and effectively improving the likelihood of sampling rare events based on forming small random pools of single-flow–sorted cells, amplifying their DNA by multiple displacement amplification and sequencing all cells in the pool, creating a “mini-metagenome” is developed.