N
Nils Lachmann
Researcher at Charité
Publications - 76
Citations - 2978
Nils Lachmann is an academic researcher from Charité. The author has contributed to research in topics: Transplantation & Kidney transplantation. The author has an hindex of 23, co-authored 66 publications receiving 2376 citations.
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Journal ArticleDOI
Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation.
Brian D. Tait,Caner Süsal,Howard M. Gebel,Peter Nickerson,Andrea A. Zachary,Frans H.J. Claas,Elaine F. Reed,Robert A. Bray,Patricia Campbell,Jeremy R. Chapman,P. Toby Coates,Robert B. Colvin,Emanuele Cozzi,Ilias I.N. Doxiadis,Susan V. Fuggle,John S. Gill,Denis Glotz,Nils Lachmann,Thalachallour Mohanakumar,Nicole Suciu-Foca,Suchitra Sumitran-Holgersson,Kazunari Tanabe,Craig J. Taylor,Dolly B. Tyan,Angela C Webster,Adriana Zeevi,Gerhard Opelz +26 more
TL;DR: A group of laboratory and clinical experts in the field of transplantation was convened to prepare a consensus report and make recommendations on the use of this new technology based on both published evidence and expert opinion.
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Anti-human leukocyte antigen and donor-specific antibodies detected by luminex posttransplant serve as biomarkers for chronic rejection of renal allografts.
Nils Lachmann,Paul I. Terasaki,Klemens Budde,Lutz Liefeldt,Andreas Kahl,Petra Reinke,Johann Pratschke,Birgit Rudolph,Danilo Schmidt,Abdulgabar Salama,Constanze Schönemann +10 more
TL;DR: It is confirmed that HLAab produced even late after transplantation are detrimental to graft outcome, and DSA were proven to have a strong adverse impact on graft survival.
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Donor‐Specific HLA Antibodies in a Cohort Comparing Everolimus With Cyclosporine After Kidney Transplantation
Lutz Liefeldt,Susanne Brakemeier,Petra Glander,Johannes Waiser,Nils Lachmann,Constanze Schönemann,Bianca Zukunft,P. Illigens,Danilo Schmidt,Kaiyin Wu,Birgit Rudolph,H.-H. Neumayer,Klemens Budde +12 more
TL;DR: It is demonstrated for the first time that everolimus‐based immunosuppression is associated with an increased risk for the development of DSA and AMR.
Journal ArticleDOI
Comparison between bortezomib and rituximab in the treatment of antibody-mediated renal allograft rejection
Johannes Waiser,Klemens Budde,Manuela Schütz,Lutz Liefeldt,Birgit Rudolph,Constanze Schönemann,Hans-H. Neumayer,Nils Lachmann +7 more
TL;DR: Treatment of ABMR with bortezomib in addition to standard therapy was partially effective, whereas treatment with a fixed dose of rituximab in addition of standard therapy with PPH and IVIG did not result in sufficient long-term graft survival.
Journal ArticleDOI
Non-HLA antibodies targeting vascular receptors enhance alloimmune response and microvasculopathy after heart transplantation.
Nicola E. Hiemann,Rudolf Meyer,Ernst Wellnhofer,Constanze Schoenemann,Harald Heidecke,Nils Lachmann,Roland Hetzer,Duska Dragun +7 more
TL;DR: Elevated levels of AT1R and ETAR Abs are associated with cellular and Ab-mediated rejection and early onset of microvasculopathy and should be routinely monitored after heart transplantation.