C
Constanze Schönemann
Researcher at Charité
Publications - 69
Citations - 3663
Constanze Schönemann is an academic researcher from Charité. The author has contributed to research in topics: Transplantation & Human leukocyte antigen. The author has an hindex of 26, co-authored 69 publications receiving 3405 citations. Previous affiliations of Constanze Schönemann include Massachusetts Institute of Technology.
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Journal ArticleDOI
Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection.
Duska Dragun,Dominik N. Müller,Jan Hinrich Bräsen,Lutz Fritsche,Melina Nieminen-Kelhä,Ralf Dechend,Ulrich Kintscher,Birgit Rudolph,Johan Hoebeke,Diana Eckert,Istvan Mazak,Ralph Plehm,Constanze Schönemann,Thomas Unger,Klemens Budde,Hans-Hellmut Neumayer,Friedrich C. Luft,Gerd Wallukat +17 more
TL;DR: A non-HLA, AT1-receptor-mediated pathway may contribute to refractory vascular rejection, and affected patients might benefit from removal of At1- receptor antibodies or from pharmacologic blockade of AT1 receptors.
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Anti-human leukocyte antigen and donor-specific antibodies detected by luminex posttransplant serve as biomarkers for chronic rejection of renal allografts.
Nils Lachmann,Paul I. Terasaki,Klemens Budde,Lutz Liefeldt,Andreas Kahl,Petra Reinke,Johann Pratschke,Birgit Rudolph,Danilo Schmidt,Abdulgabar Salama,Constanze Schönemann +10 more
TL;DR: It is confirmed that HLAab produced even late after transplantation are detrimental to graft outcome, and DSA were proven to have a strong adverse impact on graft survival.
Journal ArticleDOI
Target Structures of the CD8+-T-Cell Response to Human Cytomegalovirus: the 72-Kilodalton Major Immediate-Early Protein Revisited
Florian Kern,Ingolf Surel,Nicole Faulhaber,Claudia Frömmel,Jens Schneider-Mergener,Constanze Schönemann,Petra Reinke,Hans-Dieter Volk +7 more
TL;DR: The results suggest that IE-1 is far more important as a CD8+-T-cell target than current opinion suggests.
Journal ArticleDOI
Analysis of CD8 T cell reactivity to cytomegalovirus using protein-spanning pools of overlapping pentadecapeptides.
Florian Kern,Nicole Faulhaber,Claudia Frömmel,Elham Khatamzas,Susanna Prösch,Constanze Schönemann,Ines Kretzschmar,Rudolf Volkmer-Engert,Hans-Dieter Volk,Petra Reinke +9 more
TL;DR: The results confirmed the previous contention that HCMV IE‐1 is an important CD8 T cell target and the technical improvement made in order to address this question has clearly wider implications.
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Donor‐Specific HLA Antibodies in a Cohort Comparing Everolimus With Cyclosporine After Kidney Transplantation
Lutz Liefeldt,Susanne Brakemeier,Petra Glander,Johannes Waiser,Nils Lachmann,Constanze Schönemann,Bianca Zukunft,P. Illigens,Danilo Schmidt,Kaiyin Wu,Birgit Rudolph,H.-H. Neumayer,Klemens Budde +12 more
TL;DR: It is demonstrated for the first time that everolimus‐based immunosuppression is associated with an increased risk for the development of DSA and AMR.