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Nissi Varki

Researcher at University of California, San Diego

Publications -  193
Citations -  18035

Nissi Varki is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Sialic acid & Antibody. The author has an hindex of 75, co-authored 188 publications receiving 16502 citations. Previous affiliations of Nissi Varki include University of California, Berkeley & University of Chicago.

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Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody

TL;DR: The distribution of tissue factor antigen as demonstrated by immunostaining supports the hypothesis that maintenance of a physical barrier between tissue factor activity and blood is key to the normal regulation of hemostasis.
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Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis

TL;DR: L-selectin on neutrophils, monocytes, and/or NK cells has a role in facilitating metastasis, acting beyond the early time points wherein P- selectin mediates interactions of platelet with tumor cells.
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Molecular basis of metastasis.

TL;DR: The data indicate that although the number of normal-appearing osteoclasts is significantly increased in patients receiving bisphosphonate therapy, as compared with those receiving placebo, the decrease in biochemical markers and increase in bone density suggest that even normal- Apps may resorb bone poorly, andconsiderable evidence indicates that osteoclast are formed by fusion of mononuclear precursors.
Journal Article

Detection of ganglioside GD2 in tumor tissues and sera of neuroblastoma patients.

TL;DR: The GD2 serum level of one neuroblastoma patient, when followed serially, was found to correlate with progression of disease, suggesting the potential usefulness of this assay for the diagnosis and monitoring of Neuroblastoma.
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The Ashwell receptor mitigates the lethal coagulopathy of sepsis

TL;DR: Internal ligands of the Ashwell receptor are identified as glycoproteins and regulatory components in blood coagulation and thrombosis that include von Willebrand factor (vWF) and platelets and improves the probability of host survival.