Nivedita Sahu

TL;DR: This is the first demonstration of a successful strategy to inhibit tumor STAT3 signaling via systemic administration of a selective STAT3 inhibitor, thereby paving the way for broad clinical development and having therapeutic implications beyond STAT3 to other “undruggable” targets in human cancers.

TL;DR: An appreciation is gained for the current advances in biomarker discovery using advanced technology and data interpretation in microarray analysis and proteomics and other molecular targets, aside from epidermal growth factor receptor, are discussed in the context of their promising role in predicting recurrence, response to therapy, survival, and overall prognosis.

TL;DR: In this study, respiratory viruses were more commonly isolated from patients with CRS compared with healthy controls, and viral infection may play a greater role in symptom exacerbation in C RSsNP than in CRSwNP.

TL;DR: Respiratory viral detection is more commonly detected in the paranasal sinuses of patients with CF compared with healthy controls and this findings may provide insight into the pathophysiology of CF and open new avenues for potential targeted therapy.

TL;DR: A case of fibroma treated by surgical excision is presented, which represents hyperplasias instead of true neoplasm, which develops due to irritation to the mucosal tissue resulting in proliferation of the cells.