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Norbert Müller

Researcher at Ludwig Maximilian University of Munich

Publications -  360
Citations -  15394

Norbert Müller is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Schizophrenia & Spin polarization. The author has an hindex of 61, co-authored 355 publications receiving 13843 citations. Previous affiliations of Norbert Müller include Max Planck Society & University of Osnabrück.

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Attosecond spectroscopy in condensed matter

TL;DR: The ability to obtain direct time-domain access to charge dynamics with attosecond resolution by probing photoelectron emission from single-crystal tungsten is demonstrated and illustrates thatAttosecond metrology constitutes a powerful tool for exploring not only gas-phase systems, but also fundamental electronic processes occurring on the attose Cond timescale in condensed-matter systems and on surfaces.
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The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine.

TL;DR: The fact that treatment with an anti-inflammatory drug showed beneficial effects on MD indicates that inflammation is related to the pathomechanism of the disorder, although the exact mechanisms remain to become elucidated.
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The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression

TL;DR: A hypothesis integrating current concepts of neurotransmission and hypothalamus–pituitary–adrenal (HPA) axis dysregulation with findings on immunological alterations and alterations in brain morphology in MD is presented.
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Beneficial antipsychotic effects of celecoxib add-on therapy compared to risperidone alone in schizophrenia.

TL;DR: Additional treatment with celecoxib has significant positive effects on the therapeutic action of risperidone with regard to total schizophrenia psychopathology, indicating that immune dysfunction in schizophrenia is not just an epiphenomenon but is related to the pathomechanism of the disorder.
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Inflammation in Schizophrenia: Pathogenetic Aspects and Therapeutic Considerations.

TL;DR: Support for the relevance of a low-level neuroinflammatory process in schizophrenia is provided by the loss of central nervous system volume and microglial activation demonstrated in neuroimaging studies, and the benefit of anti-inflammatory medications found in some studies and the intrinsic anti- inflammatory and immunomodulatory effects of antipsychotics provide further support for the role of inflammation in this debilitating disease.