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Volker Arolt
Researcher at University of Münster
Publications - 144
Citations - 17762
Volker Arolt is an academic researcher from University of Münster. The author has contributed to research in topics: Major depressive disorder & Medicine. The author has an hindex of 64, co-authored 128 publications receiving 14577 citations. Previous affiliations of Volker Arolt include James Cook University & University of Texas Southwestern Medical Center.
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Journal ArticleDOI
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Naomi R. Wray,Stephan Ripke,Stephan Ripke,Stephan Ripke,Manuel Mattheisen,Maciej Trzaskowski,Enda M. Byrne,Abdel Abdellaoui,Mark Adams,Esben Agerbo,Esben Agerbo,Tracy Air,Till M.F. Andlauer,Silviu Alin Bacanu,Marie Bækvad-Hansen,Marie Bækvad-Hansen,Aartjan F.T. Beekman,Tim B. Bigdeli,Elisabeth B. Binder,Elisabeth B. Binder,Douglas Blackwood,Julien Bryois,Henriette N. Buttenschøn,Henriette N. Buttenschøn,Jonas Bybjerg-Grauholm,Jonas Bybjerg-Grauholm,Na Cai,Na Cai,Enrique Castelao,Jane H. Christensen,Jane H. Christensen,Toni-Kim Clarke,Jonathan I.R. Coleman,Lucía Colodro-Conde,Baptiste Couvy-Duchesne,Nicholas John Craddock,Gregory E. Crawford,Cheynna A. Crowley,Hassan S. Dashti,Hassan S. Dashti,Gail Davies,Ian J. Deary,Franziska Degenhardt,Eske M. Derks,Nese Direk,Nese Direk,Conor V. Dolan,Erin C. Dunn,Erin C. Dunn,Thalia C. Eley,Nicholas Eriksson,Valentina Escott-Price,Farnush Hassan Farhadi Kiadeh,Hilary K. Finucane,Hilary K. Finucane,Andreas J. Forstner,Josef Frank,Helena Gaspar,Michael Gill,Paola Giusti-Rodríguez,Fernando S. Goes,Scott D. Gordon,Jakob Grove,Lynsey S. Hall,Lynsey S. Hall,Eilis Hannon,Christine Søholm Hansen,Christine Søholm Hansen,Thomas Hansen,Thomas Hansen,Stefan Herms,Stefan Herms,Ian B. Hickie,Per Hoffmann,Per Hoffmann,Georg Homuth,Carsten Horn,Jouke-Jan Hottenga,David M. Hougaard,David M. Hougaard,Ming Hu,Craig L. Hyde,Marcus Ising,Rick Jansen,Fulai Jin,Eric Jorgenson,James A. Knowles,Isaac S. Kohane,Isaac S. Kohane,Isaac S. Kohane,Julia Kraft,Warren W. Kretzschmar,Jesper Krogh,Zoltán Kutalik,Zoltán Kutalik,Jacqueline M. Lane,Jacqueline M. Lane,Yihan Li,Yun Li,Penelope A. Lind,Xiaoxiao Liu,Leina Lu,Donald J. MacIntyre,Dean F. MacKinnon,Robert Maier,Wolfgang Maier,Jonathan Marchini,Hamdi Mbarek,Patrick J. McGrath,Peter McGuffin,Sarah E. Medland,Divya Mehta,Divya Mehta,Christel M. Middeldorp,Christel M. Middeldorp,Evelin Mihailov,Yuri Milaneschi,Lili Milani,Jonathan Mill,Francis M. Mondimore,Grant W. Montgomery,Sara Mostafavi,Niamh Mullins,Matthias Nauck,Bernard Ng,Michel G. Nivard,Dale R. Nyholt,Paul F. O'Reilly,Hogni Oskarsson,Michael John Owen,Jodie N. Painter,Carsten Bøcker Pedersen,Carsten Bøcker Pedersen,Marianne Giørtz Pedersen,Marianne Giørtz Pedersen,Roseann E. Peterson,Erik Pettersson,Wouter J. Peyrot,Giorgio Pistis,Danielle Posthuma,Shaun Purcell,Jorge A. Quiroz,Per Qvist,Per Qvist,John P. Rice,Brien P. Riley,Margarita Rivera,Margarita Rivera,Saira Saeed Mirza,Richa Saxena,Richa Saxena,Robert A. Schoevers,Eva C. Schulte,Ling Shen,Jianxin Shi,Stanley I. Shyn,Engilbert Sigurdsson,Grant Sinnamon,Johannes H. Smit,Daniel J. Smith,Hreinn Stefansson,Stacy Steinberg,Craig A. Stockmeier,Fabian Streit,Jana Strohmaier,Katherine E. Tansey,Henning Teismann,Alexander Teumer,Wesley K. Thompson,Pippa A. Thomson,Thorgeir E. Thorgeirsson,Chao Tian,Matthew Traylor,Jens Treutlein,Vassily Trubetskoy,André G. Uitterlinden,Daniel Umbricht,Sandra Van der Auwera,Albert M. van Hemert,Alexander Viktorin,Peter M. Visscher,Yunpeng Wang,Yunpeng Wang,Yunpeng Wang,Bradley T. Webb,Shantel Weinsheimer,Shantel Weinsheimer,Jürgen Wellmann,Gonneke Willemsen,Stephanie H. Witt,Yang Wu,Hualin S. Xi,Jian Yang,Futao Zhang,Volker Arolt,Bernhard T. Baune,Klaus Berger,Dorret I. Boomsma,Sven Cichon,Udo Dannlowski,E. C.J. De Geus,J. Raymond DePaulo,Enrico Domenici,Katharina Domschke,Tõnu Esko,Tõnu Esko,Hans J. Grabe,Steven P. Hamilton,Caroline Hayward,Andrew C. Heath,David A. Hinds,Kenneth S. Kendler,Stefan Kloiber,Stefan Kloiber,Stefan Kloiber,Glyn Lewis,Qingqin S. Li,Susanne Lucae,Pamela F.A. Madden,Patrik K. E. Magnusson,Nicholas G. Martin,Andrew M. McIntosh,Andres Metspalu,Ole Mors,Ole Mors,Preben Bo Mortensen,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Merete Nordentoft,Merete Nordentoft,Markus M. Nöthen,Michael Conlon O'Donovan,Sara A. Paciga,Nancy L. Pedersen,Brenda W.J.H. Penninx,Roy H. Perlis,David J. Porteous,James B. Potash,Martin Preisig,Marcella Rietschel,Catherine Schaefer,Thomas G. Schulze,Jordan W. Smoller,Jordan W. Smoller,Kari Stefansson,Kari Stefansson,Henning Tiemeier,Rudolf Uher,Henry Völzke,Myrna M. Weissman,Myrna M. Weissman,Thomas Werge,Thomas Werge,Thomas Werge,Ashley R. Winslow,Ashley R. Winslow,Cathryn M. Lewis,Douglas F. Levinson,Gerome Breen,Anders D. Børglum,Anders D. Børglum,Patrick F. Sullivan,Patrick F. Sullivan +262 more
TL;DR: A genome-wide association meta-analysis of individuals with clinically assessed or self-reported depression identifies 44 independent and significant loci and finds important relationships of genetic risk for major depression with educational attainment, body mass, and schizophrenia.
Journal ArticleDOI
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
David M. Howard,Mark Adams,Toni-Kim Clarke,Jonathan D. Hafferty,Jude Gibson,Masoud Shirali,Jonathan R. I. Coleman,Jonathan R. I. Coleman,Saskia P. Hagenaars,Saskia P. Hagenaars,Joey Ward,Eleanor M. Wigmore,Clara Alloza,Xueyi Shen,Miruna C. Barbu,Eileen Y. Xu,Heather C. Whalley,Riccardo E. Marioni,David J. Porteous,Gail Davies,Ian J. Deary,Gibran Hemani,Klaus Berger,Henning Teismann,Rajesh Rawal,Volker Arolt,Bernhard T. Baune,Udo Dannlowski,Katharina Domschke,Chao Tian,David A. Hinds,Maciej Trzaskowski,Enda M. Byrne,Stephan Ripke,Stephan Ripke,Stephan Ripke,Daniel J. Smith,Patrick F. Sullivan,Patrick F. Sullivan,Naomi R. Wray,Gerome Breen,Gerome Breen,Cathryn M. Lewis,Cathryn M. Lewis,Andrew M. McIntosh,Andrew M. McIntosh +45 more
TL;DR: A genetic meta-analysis of depression found 269 associated genes that highlight several potential drug repositioning opportunities, and relationships with depression were found for neuroticism and smoking.
Journal ArticleDOI
Limbic Scars: Long-Term Consequences of Childhood Maltreatment Revealed by Functional and Structural Magnetic Resonance Imaging
Udo Dannlowski,Anja Stuhrmann,Victoria Beutelmann,Peter Zwanzger,Thomas Lenzen,Dominik Grotegerd,Katharina Domschke,Christa Hohoff,Patricia Ohrmann,Jochen Bauer,Christian Lindner,Christian Postert,Carsten Konrad,Volker Arolt,Walter Heindel,Thomas Suslow,Thomas Suslow,Harald Kugel +17 more
TL;DR: The present results might suggest that limbic hyperresponsiveness and reduced hippocampal volumes could be mediators between the experiences of adversities during childhood and the development of emotional disorders.
Journal ArticleDOI
Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group.
Lianne Schmaal,Derrek P. Hibar,Philipp G. Sämann,Geoffrey B. Hall,Bernhard T. Baune,Neda Jahanshad,Joshua W. Cheung,T.G.M. van Erp,Daniel Bos,M. A. Ikram,Meike W. Vernooij,Wiro J. Niessen,Wiro J. Niessen,Henning Tiemeier,Henning Tiemeier,A. Hofman,Katharina Wittfeld,Hans-Jörgen Grabe,Hans-Jörgen Grabe,Deborah Janowitz,Robin Bülow,M Selonke,Henry Völzke,Dominik Grotegerd,Udo Dannlowski,Udo Dannlowski,Volker Arolt,Nils Opel,Walter Heindel,Harald Kugel,D. Hoehn,Michael Czisch,Baptiste Couvy-Duchesne,Baptiste Couvy-Duchesne,Miguel E. Rentería,Lachlan T. Strike,Margaret J. Wright,Natalie T. Mills,Natalie T. Mills,G.I. de Zubicaray,Katie L. McMahon,Sarah E. Medland,Nicholas G. Martin,Nathan A. Gillespie,Roberto Goya-Maldonado,Oliver Gruber,Bernd Krämer,Sean N. Hatton,Jim Lagopoulos,Ian B. Hickie,Thomas Frodl,Thomas Frodl,Angela Carballedo,Eva-Maria Frey,L. S. van Velzen,B.W.J.H. Penninx,M-J van Tol,N.J. van der Wee,Christopher G. Davey,Ben J. Harrison,Benson Mwangi,Bo Cao,Jair C. Soares,Ilya M. Veer,Henrik Walter,D. Schoepf,Bartosz Zurowski,Carsten Konrad,Elisabeth Schramm,Claus Normann,Knut Schnell,Matthew D. Sacchet,Ian H. Gotlib,Glenda MacQueen,Beata R. Godlewska,Thomas Nickson,Andrew M. McIntosh,Andrew M. McIntosh,Martina Papmeyer,Martina Papmeyer,Heather C. Whalley,Jeremy Hall,Jeremy Hall,J.E. Sussmann,Meng Li,Martin Walter,Martin Walter,Lyubomir I. Aftanas,Ivan Brack,Nikolay A. Bokhan,Nikolay A. Bokhan,Nikolay A. Bokhan,Paul M. Thompson,Dick J. Veltman +93 more
TL;DR: In this article, the authors present the largest ever worldwide study by the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Major Depressive Disorder Working Group on cortical structural alterations in MDD.
Journal ArticleDOI
The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine.
Norbert Müller,Markus J. Schwarz,Sandra Dehning,A. Douhe,A. Cerovecki,B. Goldstein-Müller,Ilja Spellmann,G. Hetzel,Katja Maino,N. Kleindienst,Hans-Jürgen Möller,Volker Arolt,Michael Riedel +12 more
TL;DR: The fact that treatment with an anti-inflammatory drug showed beneficial effects on MD indicates that inflammation is related to the pathomechanism of the disorder, although the exact mechanisms remain to become elucidated.