N
Noushin Dianat
Researcher at University of Paris-Sud
Publications - 11
Citations - 379
Noushin Dianat is an academic researcher from University of Paris-Sud. The author has contributed to research in topics: Induced pluripotent stem cell & Embryonic stem cell. The author has an hindex of 6, co-authored 8 publications receiving 332 citations. Previous affiliations of Noushin Dianat include French Institute of Health and Medical Research.
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Journal ArticleDOI
Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells
Noushin Dianat,Hélène Dubois-Pot-Schneider,Clara Steichen,Christophe Desterke,Philippe Leclerc,Aurélien Raveux,Laurent Combettes,Anne Weber,Anne Corlu,Anne Dubart-Kupperschmitt +9 more
TL;DR: A robust and efficient method for differentiating pluripotent stem cells into cholangiocyte‐like cells, which display structural and functional similarities to bile duct cells in normal liver, is developed.
Journal ArticleDOI
The potential of induced pluripotent stem cell derived hepatocytes
Zara Hannoun,Clara Steichen,Noushin Dianat,Anne Weber,Anne Dubart-Kupperschmitt,Anne Dubart-Kupperschmitt +5 more
TL;DR: The potential applications and existing limitations of hiPSC-derived hepatocytes in regenerative medicine, drug screening, in vitro disease modelling and bioartificial livers are discussed.
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Human Pluripotent Stem Cells for Modelling Human Liver Diseases and Cell Therapy
TL;DR: The present progresses, limits and challenges for the generation of functional hepatocytes from human pluripotent stem cells in view of their potential use in regenerative medicine and drug discovery are reviewed.
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Messenger RNA- Versus Retrovirus-Based Induced Pluripotent Stem Cell Reprogramming Strategies: Analysis of Genomic Integrity
Clara Steichen,Clara Steichen,Eléanor Luce,Eléanor Luce,Jérome Maluenda,Lucie Tosca,Inmaculada Moreno-Gimeno,Christophe Desterke,Christophe Desterke,Noushin Dianat,Noushin Dianat,Sylvie Goulinet-Mainot,Sylvie Goulinet-Mainot,Sarah Awan-Toor,Sarah Awan-Toor,Deborah J. Burks,Joëlle Marie,Anne Weber,Anne Weber,Gérard Tachdjian,Judith Melki,Anne Dubart-Kupperschmitt,Anne Dubart-Kupperschmitt +22 more
TL;DR: The integration‐free hepatoblasts that were generated constitute a new tool for the study of diseased hepatocytes derived from patients' iPSCs and their use in the context of stem cell‐derived hepatocyte transplantation.
Journal ArticleDOI
Integration-deficient lentivectors: an effective strategy to purify and differentiate human embryonic stem cell-derived hepatic progenitors
Guanghua Yang,Guanghua Yang,Karim Si-Tayeb,Karim Si-Tayeb,Sébastien Corbineau,Sébastien Corbineau,Rémi Vernet,Régis Gayon,Noushin Dianat,Noushin Dianat,Clémence Martinet,Clémence Martinet,Denis Clay,Denis Clay,Sylvie Goulinet-Mainot,Sylvie Goulinet-Mainot,Gérard Tachdjian,Deborah J. Burks,Ludovic Vallier,Pascale Bouillé,Anne Dubart-Kupperschmitt,Anne Dubart-Kupperschmitt,Anne Weber,Anne Weber +23 more
TL;DR: An effective strategy to purify human hepatic cells from cultures of differentiating hPSCs is developed, producing a novel tool that could be used not only for cell therapy but also for in vitro applications such as drug screening.