A
Anne Weber
Researcher at French Institute of Health and Medical Research
Publications - 105
Citations - 5450
Anne Weber is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Transplantation & Urinary incontinence. The author has an hindex of 36, co-authored 104 publications receiving 5118 citations. Previous affiliations of Anne Weber include University of Paris & National Institutes of Health.
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Journal ArticleDOI
Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells
S. Tamir Rashid,Sébastien Corbineau,Nicholas R.F. Hannan,Stefan J. Marciniak,Elena Miranda,Graeme J.M. Alexander,Isabel Huang-Doran,Julian L. Griffin,Lars Ährlund-Richter,Jeremy N. Skepper,Robert K. Semple,Anne Weber,David A. Lomas,Ludovic Vallier +13 more
TL;DR: These patient-derived hepatocytes demonstrate that it is possible to model diseases whose phenotypes are caused by pathological dysregulation of key processes within adult cells, and a simple and effective platform for hepatocyte generation from patient-specific human iPS cells.
Journal ArticleDOI
Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development
Thomas Touboul,Nicholas R.F. Hannan,Sébastien Corbineau,Amelie Martinez,Clémence Martinet,Sophie Branchereau,Sylvie Mainot,Helene Strick-Marchand,Roger A. Pedersen,James P. Di Santo,Anne Weber,Ludovic Vallier +11 more
TL;DR: A robust and efficient method to differentiate pluripotent stem cells into hepatic cells, which exhibit characteristics of human hepatocytes are reported, which should facilitate the development of clinical grade hepatocytes for transplantation and for research on drug discovery.
Journal ArticleDOI
The standardization of terminology for researchers in female pelvic floor disorders.
Anne Weber,Paul Abrams,Linda Brubaker,Geoffrey W. Cundiff,G. D. Davis,R. R. Dmochowski,John R. Fischer,Tracy L. Hull,Ingrid Nygaard,Alison C. Weidner +9 more
TL;DR: A standard terminology for research on pelvic floor disorders is presented and areas of high priority for future research are identified.
Journal ArticleDOI
Refractory Idiopathic Urge Urinary Incontinence and Botulinum A Injection
Linda Brubaker,Holly E. Richter,Anthony G. Visco,S.T. Mahajan,Ingrid Nygaard,Thomas Braun,Matthew D. Barber,Shawn A. Menefee,Joseph I. Schaffer,Anne Weber,John T. Wei +10 more
TL;DR: Local injection of 200 U botulinum toxin A was an effective and durable treatment for refractory overactive bladder, however, a transient post-void residual urine increase was experienced in 43% of patients.
Journal ArticleDOI
Early Cell Fate Decisions of Human Embryonic Stem Cells and Mouse Epiblast Stem Cells Are Controlled by the Same Signalling Pathways
Ludovic Vallier,Thomas Touboul,Thomas Touboul,Zhenzhi Chng,Minodora Brimpari,Nicholas R.F. Hannan,Enrique Millan,Lucy E. Smithers,Matthew Trotter,Peter J. Rugg-Gunn,Anne Weber,Roger A. Pedersen +11 more
TL;DR: The defined growth factor conditions described here represent an essential step toward the production of mature cell types from pluripotent stem cells in conditions fully compatible with clinical use ant also provide a general approach for modelling the early steps of mammalian embryonic development.