C
Clara Steichen
Researcher at French Institute of Health and Medical Research
Publications - 17
Citations - 579
Clara Steichen is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Induced pluripotent stem cell & Transplantation. The author has an hindex of 7, co-authored 15 publications receiving 511 citations. Previous affiliations of Clara Steichen include University of Poitiers & University of Paris-Sud.
Papers
More filters
Journal ArticleDOI
Barriers and Advances in Kidney Preservation
Clara Steichen,Clara Steichen,Sébastien Giraud,Sébastien Giraud,Delphine Bon,Delphine Bon,Benoit Barrou,Lionel Badet,E. Salame,Thomas Kerforne,Géraldine Allain,J. Roumy,Christophe Jayle,Christophe Jayle,Patrick Hannaert,Patrick Hannaert,Thierry Hauet,R. Thuillier +17 more
TL;DR: In this article, the authors present existing barriers in transplantation (e.g., temperature adjustment and adequate protocol, interest for oxygen addition during preservation, and clear procedure for organ perfusion during machine preservation) and expose the importance of identifying reliable biomarkers to monitor graft quality and predict short and long-term outcomes.
Journal ArticleDOI
The potential of induced pluripotent stem cell derived hepatocytes
Zara Hannoun,Clara Steichen,Noushin Dianat,Anne Weber,Anne Dubart-Kupperschmitt,Anne Dubart-Kupperschmitt +5 more
TL;DR: The potential applications and existing limitations of hiPSC-derived hepatocytes in regenerative medicine, drug screening, in vitro disease modelling and bioartificial livers are discussed.
Journal ArticleDOI
Messenger RNA- Versus Retrovirus-Based Induced Pluripotent Stem Cell Reprogramming Strategies: Analysis of Genomic Integrity
Clara Steichen,Clara Steichen,Eléanor Luce,Eléanor Luce,Jérome Maluenda,Lucie Tosca,Inmaculada Moreno-Gimeno,Christophe Desterke,Christophe Desterke,Noushin Dianat,Noushin Dianat,Sylvie Goulinet-Mainot,Sylvie Goulinet-Mainot,Sarah Awan-Toor,Sarah Awan-Toor,Deborah J. Burks,Joëlle Marie,Anne Weber,Anne Weber,Gérard Tachdjian,Judith Melki,Anne Dubart-Kupperschmitt,Anne Dubart-Kupperschmitt +22 more
TL;DR: The integration‐free hepatoblasts that were generated constitute a new tool for the study of diseased hepatocytes derived from patients' iPSCs and their use in the context of stem cell‐derived hepatocyte transplantation.
Journal ArticleDOI
Urine-derived stem/progenitor cells: A focus on their characterization and potential.
TL;DR: This review will describe the isolation and characterization of urine-derived stem cells (USCs), and specifically present USC phenotype, which is not an object of consensus in the literature, as well as detail their differentiation capacity.
Journal ArticleDOI
Dynamic transcriptomic analysis of Ischemic Injury in a Porcine Pre-Clinical Model mimicking Donors Deceased after Circulatory Death
Sébastien Giraud,Sébastien Giraud,Clara Steichen,Clara Steichen,Géraldine Allain,Géraldine Allain,Pierre Couturier,Delphine Labourdette,Sophie Lamarre,Virginie Ameteau,Virginie Ameteau,Solenne Tillet,Solenne Tillet,Patrick Hannaert,Raphael Thuillier,Raphael Thuillier,Thierry Hauet +16 more
TL;DR: A dynamic transcriptomic analysis of preclinical porcine model kidneys subjected to ischemic stress mimicking DCD donor uncovered targets which will be validated as biomarkers and new therapeutic targets to optimize graft kidney quality before transplantation and improve whole transplantation outcome.