N
Nripendra N. Mishra
Researcher at Central Drug Research Institute
Publications - 30
Citations - 879
Nripendra N. Mishra is an academic researcher from Central Drug Research Institute. The author has contributed to research in topics: Antibacterial activity & Antibacterial agent. The author has an hindex of 16, co-authored 28 publications receiving 760 citations. Previous affiliations of Nripendra N. Mishra include University of Lucknow & B.P. Koirala Institute of Health Sciences.
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Journal ArticleDOI
Synthesis and antifungal activity of 1,2,3-triazole containing fluconazole analogues.
Nilkanth G. Aher,Vandana S. Pore,Nripendra N. Mishra,Awanit Kumar,Praveen K. Shukla,Aanchal Sharma,Manoj Kumar Bhat +6 more
TL;DR: The studies presented here provide structural modification of fluconazole to give 1,2,3-trazole containing molecules which were evaluated in vivo against Candida albicans intravenous challenge in Swiss mice and antiproliferative activities were tested against human hepatocellular carcinoma Hep3B and human epithelial carcinoma A431.
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Design, synthesis and biological evaluation of novel nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents
TL;DR: The results indicate that compounds 3b, 5a and 5b have potent antifungal activity and amongst the most promising antIFungal compounds, 3b showed better antifundal activity than clinically prevalent antif fungus drug Fluconazole.
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Anti-HSV-2 activity of Terminalia chebula Retz extract and its constituents, chebulagic and chebulinic acids.
Ajay Kesharwani,Suja Kizhiyedath Polachira,Reshmi Nair,Aakanksha Agarwal,Nripendra N. Mishra,Satish K. Gupta +5 more
TL;DR: Results presented herein suggest that T. chebula extract, chebulagic and chebulinic acids have higher direct antiviral activity against HSV-2 and efficacy to inhibit virus attachment and penetration to the host cells as compared to acyclovir, which is more potent to inhibit post-infection virus replication.
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Corneal targeted nanoparticles for sustained natamycin delivery and their PK/PD indices: an approach to reduce dose and dosing frequency.
Hardik Chandasana,Hardik Chandasana,Yarra Durga Prasad,Yashpal S. Chhonker,Yashpal S. Chhonker,Telaprolu K. Chaitanya,Nripendra N. Mishra,Kalyan Mitra,Kalyan Mitra,Praveen K. Shukla,Rabi Sankar Bhatta,Rabi Sankar Bhatta +11 more
TL;DR: A corneal targeted nanoformulation was designed in order to reduce dose and dosing frequency of natamycin and evaluate its pharmacokinetic/pharmacodynamic indices in comparison with clinical marketed preparation.
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Synthesis and biological evaluation of glycal-derived novel tetrahydrofuran 1,2,3-triazoles by 'click' chemistry.
L. Vijaya Raghava Reddy,P. Venkat Reddy,Nripendra N. Mishra,Praveen K. Shukla,Garima Yadav,Ranjana Srivastava,Arun K. Shaw +6 more
TL;DR: Thirteen new 1,2,3-triazoles (5a-e, 15a-d, 17a-b, 19, and 21) were synthesized by 'click' reaction of sugar-derived azides with commercially available acetylenes and tested in vitro for their biological activity.