N
Nurit Zaks
Researcher at National Institutes of Health
Publications - 8
Citations - 2275
Nurit Zaks is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Familial Mediterranean fever & Pyrin domain. The author has an hindex of 8, co-authored 8 publications receiving 2192 citations.
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Journal ArticleDOI
Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever
Ivona Aksentijevich,Michael Centola,Zuoming Deng,Raman Sood,James E. Balow,Geryl Wood,Nurit Zaks,Elizabeth Mansfield,Xinguo Chen,S. Eisenberg,Anil Vedula,Neta Shafran,Nina Raben,Elon Pras,M. Pras,DL Kastner,Trevor Blake,Andreas D. Baxevanis,Christiane M. Robbins,David B. Krizman,Francis S. Collins,Paul P. Liu,Xuejun Chen,M. Shohat,Melanie Hamon,T. L. Kahan,A. Cercek,J. I. Rotter,N. FischelGhodsian,N. Richards,D. A. Shelton,D.L. Gumucio,Y. Yokoyama,Marie Mangelsdorf,A. Orsborn,Robert I. Richards,Darrell O. Ricke,J. M. Buckingham,Robert K. Moyzis,L. L. Deaven,N. A. Doggett +40 more
TL;DR: The cloning of the FMF gene promises to shed light on the regulation of acute inflammatory responses and is described as a member of a family of nuclear factors homologous to the Ro52 autoantigen.
Journal Article
Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. The International FMF Consortium.
Nurit Zaks,James E. Balow,Elizabeth Mansfield,Marie Mangelsdorf,M. Shohat,Trevor Blake,Deborah L. Gumucio,A. Orsborn,Neta Shafran,Andreas D. Baxevanis,CY Yokoyama,S.R.K. Vedula,Francis S. Collins,M. Pras,Geryl Wood,Michael Centola,Zuoming Deng,J. M. Buckingham,Melanie Hamon,Robert K. Moyzis,DL Kastner,N. Richards,Ivona Aksentijevich,Xuejun Chen,C. A. Robbins,Nina Raben,Paul P. Liu,Norman A. Doggett,T. L. Kahan,Robert I. Richards,Elon Pras,Raman Sood,S. Eisenberg +32 more
Journal Article
The prodrome : A prominent yet overlooked pre-attack manifestation of familial mediterranean fever
TL;DR: A prodromal period heralding attacks is a newly defined and reliable FMF manifestation that reproducibly predicts attacks and may help prevent attacks and elucidate the pathogenesis of the disease.
Journal ArticleDOI
A High-Resolution Genetic Map of the Familial Mediterranean Fever Candidate Region Allows Identification of Haplotype-Sharing among Ethnic Groups ☆
James E. Balow,James E. Balow,David A. Shelton,Annette Orsborn,Marie Mangelsdorf,Ivona Aksentijevich,Trevor Blake,Raman Sood,Dawn Gardner,Raymond Liu,Elon Pras,Ernesto N. Levy,Michael Centola,Zuoming Deng,Nurit Zaks,Geryl Wood,Xiaoguang Chen,Neil Richards,Mordechai Shohat,Avi Livneh,Mordechai Pras,Norman A. Doggett,Francis S. Collins,Pengfei Liu,Jerome I. Rotter,Nathan Fischel-Ghodsian,Deborah L. Gumucio,Robert I. Richards,Daniel L. Kastner +28 more
TL;DR: Genotype data for 12 markers from the authors' physical map support the view that a few major mutations account for a large percentage of the cases of FMF and suggest that some of these mutations arose before the affected Middle Eastern populations diverged from one another.
Journal ArticleDOI
Construction of a 1-Mb restriction-mapped cosmid contig containing the candidate region for the familial Mediterranean fever locus (MEFV) on chromosome 16p13.3
Raman Sood,Trevor Blake,Ivona Aksentijevich,Geryl Wood,Xiang Chen,Dawn Gardner,David A. Shelton,Marie Mangelsdorf,Annette Orsborn,Elon Pras,James E. Balow,Michael Centola,Zuoming Deng,Nurit Zaks,Xiaoguang Chen,Neil Richards,Nathan Fischel-Ghodsian,Jerome I. Rotter,Mordechai Pras,Mordechai Shohat,Larry L. Deaven,Deborah L. Gumucio,David F. Callen,Robert I. Richards,Francis S. Collins,Pengfei Liu,Daniel L. Kastner,Norman A. Doggett +27 more
TL;DR: The assembly and restriction map of a 1.05-Mb cosmid contig spanning the candidate region for familial Mediterranean fever (FMF) provides an ideal resource for transcriptional mapping toward the eventual identification of this disease gene.