Ole Lederballe Pedersen

TL;DR: In no subgroup of patients were there differences in the incidence of the composite cardiac outcome with valsartan and amlodipine-based treatments, despite a greater blood pressure decrease in the amlODipine group.

TL;DR: The findings indicate that different regulatory mechanisms are activated during acute and chronic administration of nifedipine, and it is suggested that an initial rise in sympathetic activity gradually decreases during prolonged therapy, but it still remains a determinant of PRA.

TL;DR: On-treatment small artery structure identifies individuals still at increased cardiovascular risk despite long-term BP normalization and may be an additional target for therapy to prevent cardiovascular events.

TL;DR: In patients with moderate hypertension and ECG LV hypertrophy, the levels of SV and pulse pressure/SV, are associated with, and may be stimuli to different LV geometric phenotypes.

TL;DR: The results suggest that the increased heart weight, media thickness, and contractile response in mesenteric resistance vessels of SHR up to ages 23 to 27 weeks are due primarily to factors other than increased pressure.