O
Olga Lifchits
Researcher at Max Planck Society
Publications - 14
Citations - 637
Olga Lifchits is an academic researcher from Max Planck Society. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 7, co-authored 14 publications receiving 568 citations. Previous affiliations of Olga Lifchits include Université de Montréal & University of Toronto.
Papers
More filters
Journal ArticleDOI
A mild procedure for the Lewis acid-catalyzed ring-opening of activated cyclopropanes with amine nucleophiles.
Olga Lifchits,André B. Charette +1 more
TL;DR: The Lewis acid-catalyzed ring-opening of methyl 1-nitrocyclopropanecarboxylates with amine nucleophiles is described and the methodology was applied in an enantioselective synthesis of the dual serotonin/norepinephrine reuptake inhibitor.
Journal ArticleDOI
Catalytic Asymmetric Epoxidation of α-Branched Enals
TL;DR: An asymmetric catalytic epoxidation of alpha-branched, alpha, beta-unsaturated aldehydes is presented and a highly synergistic combination of a primary cinchona-based amine and a chiral phosphoric acid was found to promote the reaction with excellent enantiocontrol for alpha-monosubstituted and alpha,beta-disubst ituted enals.
Journal ArticleDOI
The cinchona primary amine-catalyzed asymmetric epoxidation and hydroperoxidation of α,β-unsaturated carbonyl compounds with hydrogen peroxide.
Olga Lifchits,Manuel Mahlau,Corinna M. Reisinger,Anna Lee,Christophe Farès,Iakov Polyak,Gopinadhanpillai Gopakumar,Walter Thiel,Benjamin List +8 more
TL;DR: Using cinchona alkaloid-derived primary amines as catalysts and aqueous hydrogen peroxide as the oxidant, highly enantioselective Weitz-Scheffer-type epoxidation and hydroperoxidation reactions of α,β-unsaturated carbonyl compounds are developed.
Journal ArticleDOI
Nucleophilic addition of phenol derivatives to methyl 1-nitrocyclopropanecarboxylates.
TL;DR: The methodology was applied in an enantioselective synthesis of the norepinephrine reuptake inhibitor atomoxetine (Strattera) and affords the products in good yields and with complete preservation of the enantiomeric excess at C-4.
Journal ArticleDOI
Direct Asymmetric α Benzoyloxylation of Cyclic Ketones
TL;DR: The asymmetric benzoyloxylation of cyclic ketones with dibenzoyl peroxide is efficiently catalyzed by chiral cinchona alkaloid-derived primary amines and BHT to give the corresponding α-benzoyloxy ketones, e.g. (III) or (IX), in good yields with high enantioselectivities as discussed by the authors.