O
Oliver C. Redfern
Researcher at University of Oxford
Publications - 63
Citations - 3439
Oliver C. Redfern is an academic researcher from University of Oxford. The author has contributed to research in topics: Vital signs & Early warning score. The author has an hindex of 23, co-authored 53 publications receiving 2749 citations. Previous affiliations of Oliver C. Redfern include John Radcliffe Hospital & University of Portsmouth.
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Journal ArticleDOI
Predicting protein function from sequence and structure
TL;DR: There is an increasing number of noteworthy methods for predicting protein function from sequence and structural data alone, many of which are readily available to cell biologists who are aware of the strengths and pitfalls of each available technique.
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The CATH domain structure database: new protocols and classification levels give a more comprehensive resource for exploring evolution.
Lesley H. Greene,Tony E. Lewis,Sarah Addou,Alison L. Cuff,Timothy J. Dallman,Mark Dibley,Oliver C. Redfern,Frances M. G. Pearl,Rekha Nambudiry,Adam J. Reid,Ian Sillitoe,Corin Yeats,Janet M. Thornton,Christine A. Orengo +13 more
TL;DR: There has been a 20% increase in the number of structural domains classified in CATH, up to 86 151 domains, and an update of the CATH Dictionary of homologous structures (CATH-DHS) which now contains multiple structural alignments, consensus information and functional annotations for 1459 well populated superfamilies in Cath.
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The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis
Frances M. G. Pearl,Annabel E. Todd,Ian Sillitoe,Mark Dibley,Oliver C. Redfern,Tony E. Lewis,Christopher G. Bennett,Russell L. Marsden,Alastair Grant,David A. Lee,Adrian Akpor,Michael Maibaum,Andrew Harrison,Timothy J. Dallman,Gabrielle A. Reeves,Ilhem Diboun,Sarah Addou,Stefano Lise,Caroline Johnston,Antonio Sillero,Janet M. Thornton,Christine A. Orengo +21 more
TL;DR: The CATH database of protein domain structures currently contains 43 229 domains classified into 1467 superfamilies and 5107 sequence families is expanded with sequence relatives from GenBank and completed genomes, using a variety of efficient sequence search protocols and reliable thresholds.
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What impact does nursing care left undone have on patient outcomes? Review of the literature
Alejandra Recio-Saucedo,Alejandra Recio-Saucedo,Chiara Dall'Ora,Antonello Maruotti,Antonello Maruotti,Jane Ball,Jane Ball,Jim Briggs,Paul Meredith,Oliver C. Redfern,Caroline Kovacs,David Prytherch,Gary B. Smith,Peter Griffiths,Peter Griffiths +14 more
TL;DR: The review shows the modest evidence base of studies exploring missed care and patient outcomes generated mostly from nurse and patient self‐reported data supports the assertion that nurse staffing levels and skill mix are associated with adverse outcomes as a result of missed care.
Journal ArticleDOI
The CATH classification revisited--architectures reviewed and new ways to characterize structural divergence in superfamilies.
Alison L. Cuff,Ian Sillitoe,Tony E. Lewis,Oliver C. Redfern,Richard Charles Garratt,Janet M. Thornton,Christine A. Orengo +6 more
TL;DR: The CATH architecture level has been revisited as part of the development of a ‘Protein Chart’ and information on the population of each architecture is presented and the degree of structural diversity in each superfamily and structural overlaps between superfamilies are described.