scispace - formally typeset
Search or ask a question

Showing papers by "Oliver Smithies published in 1983"

Journal Article•DOI•
Unexpected relationships between four large deletions in the human β-globin gene cluster

[...]

Elio F. Vanin1, Paula S. Henthom1, Dimitris Kioussis2, Frank Grosveld2, Oliver Smithies1 •
University of Wisconsin-Madison1, National Institute for Medical Research2
01 Dec 1983-Cell
TL;DR: It is shown, by comparing DNA sequences, that the deletions are due to non-homologous DNA exchanges, and the results suggest that the four deletions were generated by a common mechanism.

188 citations

Journal Article•DOI•
Coordinate modulation of transfected HSV thymidine kinase and human globin genes

[...]

Raymond S. Roginski1, Arthur I. Skoultchi1, Paula S. Henthorn2, Oliver Smithies2, Nancy Hsiung3, Nancy Hsiung4, Raju Kucherlapati3, Raju Kucherlapati4 •
Albert Einstein College of Medicine1, University of Wisconsin-Madison2, University of Illinois at Chicago3, Princeton University4
01 Nov 1983-Cell
TL;DR: It is concluded that genes introduced into cells by ligated cotransfection can be regulated coordinately and that the unit of this regulated expression can be at least 20 kb long.

36 citations